Nonalcoholic Fatty Liver Disease in Morbidly Obese Subjects: Correlation Among Histopathologic Findings, Biochemical Features, and Ultrasound Evaluation

被引：0
作者：
Everton Cazzo
Fabio de Felice Gallo
José Carlos Pareja
Elinton Adami Chaim
机构：
[1] Campinas State University (UNICAMP),Department of Surgery, Faculty of Medical Sciences
[2] Campinas State University (UNICAMP),Faculty of Medical Sciences
来源：
Obesity Surgery | 2014年 / 24卷
关键词：
Fatty liver; Obesity; Gastric bypass; Ultrasonography; Liver diseases;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nonalcoholic fatty liver disease (NAFLD) has become an important health issue lately. The aim of this study is to determine its prevalence among obese subjects which undergo Roux-en-Y gastric bypass (RYGB). It is a cross-sectional retrospective study involving 164 subjects who underwent RYGB. Clinical, biochemical, and histopathologic features were evaluated. The most common histopathologic features observed were steatohepatitis with fibrosis (29.9 %) and isolated fibrosis (29.3 %). Increased alkaline phosphatase was associated to NAFLD. Dyslipidemia and type 2 diabetes mellitus were associated to NAFLD. Ultrasound had a global accuracy of 78 % to detect NAFLD. Higher prevalence of severe forms of NAFLD was observed compared to previous reports. Most routine biochemical studies had poor correlation with NAFLD and ultrasound was useful but not definitive to detect NAFLD.
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页码：666 / 668
页数：2
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