Expression of Tissue Factor mRNA and Invasion of Blood Vessels by Tumor Cells in Non-Small Cell Lung Cancer

被引:0
|
作者
Yoshihiro Minamiya
Ikuo Matsuzaki
Masato Sageshima
Hajime Saito
Kousei Taguchi
Taku Nakagawa
Jun-ichi Ogawa
机构
[1] Akita University School of Medicine,Second Department of Surgery
[2] Akita University Hospital,Division of Clinical Pathology
来源
Surgery Today | 2004年 / 34卷
关键词
Tissue factor; Blood vessel invasion; Non-small cell lung cancer; Real-time quantitative reverse transcription–polymerase chain reaction; Coagulation;
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学科分类号
摘要
Purpose. Tissue factor (TF), an initiator of the extrinsic coagulation cascade, is also expressed in a wide range of cancer cells and plays an important role in cancer progression and metastasis, as well as in processes independent of the blood coagulation pathway. For example, by acting as an adhesion molecule enabling tissue invasion, TF may play a key role in the metastatic process and angiogenesis in non-small cell lung cancer (NSCLC).
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页码:1 / 5
页数:4
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