Protein-RNA interaction restricts telomerase from running through the stop sign

被引：0
|
作者：
Linghe Xi
Thomas R Cech
机构：
[1] Cellular and Developmental Biology,Linghe Xi and Thomas R. Cech are at the Department of Molecular
[2] BioFrontiers Institute,undefined
[3] and the Howard Hughes Medical Institute,undefined
[4] University of Colorado,undefined
[5] Boulder,undefined
[6] Colorado,undefined
[7] USA.,undefined
来源：
Nature Structural & Molecular Biology | 2015年 / 22卷
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学科分类号：
摘要：
Telomerase is a unique reverse transcriptase in that it repetitively uses a short piece of its RNA component as template to synthesize DNA. A new crystal structure of a part of the Tetrahymena telomerase ribonucleoprotein reveals how reverse transcription is limited to this specific template region.
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页码：835 / 836
页数：1
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