Reply: Methotrexate neurotoxicity due to drug interactions: an inadequate folinic acid effect

[1] Forster VJ(2016)Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients Cancer Chemother Pharmacol 78 1093-1096

[2] van Delft FW(2015)Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia Pediatr Blood Cancer 62 539-541

[3] Baird SF(2016)Chemotherapy pharmacodynamics and neuroimaging and neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia J Clin Oncol 34 2644-2653

[4] Mair S(2014)Inadequate folinic acid rescue after methotrexate causing neurocognitive and neuroradiological central nervous system late effects in children with acute lymphatic leukemia J Pediatr Hematol Oncol 36 501-947

[5] Skinner R(2013)Challenging the clinical relevance of folinic acid over rescue after high dose methotrexate (HDMTX) Med Hypotheses 81 942-1962

[6] Halsey C(2006)High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia Leukemia 20 1955-363

[7] Lobel U(1990)Rescue after intermediate and high-dose methotrexate: background, rationale, and current practice Pediatr Hematol Oncol 7 347-41

[8] Trah J(2009)Folate homeostasis in cerebrospinal fluid during therapy for acute lymphoblastic leukemia Pediatr Neurol 40 34-undefined

[9] Escherich G(undefined)undefined undefined undefined undefined-undefined

[10] Krull KR(undefined)undefined undefined undefined undefined-undefined

[1] Forster VJ(2016)Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients Cancer Chemother Pharmacol 78 1093-1096

[2] van Delft FW(2015)Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia Pediatr Blood Cancer 62 539-541

[3] Baird SF(2016)Chemotherapy pharmacodynamics and neuroimaging and neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia J Clin Oncol 34 2644-2653

[4] Mair S(2014)Inadequate folinic acid rescue after methotrexate causing neurocognitive and neuroradiological central nervous system late effects in children with acute lymphatic leukemia J Pediatr Hematol Oncol 36 501-947

[5] Skinner R(2013)Challenging the clinical relevance of folinic acid over rescue after high dose methotrexate (HDMTX) Med Hypotheses 81 942-1962

[6] Halsey C(2006)High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia Leukemia 20 1955-363

[7] Lobel U(1990)Rescue after intermediate and high-dose methotrexate: background, rationale, and current practice Pediatr Hematol Oncol 7 347-41

[8] Trah J(2009)Folate homeostasis in cerebrospinal fluid during therapy for acute lymphoblastic leukemia Pediatr Neurol 40 34-undefined

[9] Escherich G(undefined)undefined undefined undefined undefined-undefined

[10] Krull KR(undefined)undefined undefined undefined undefined-undefined