Fmrp targets or not: long, highly brain-expressed genes tend to be implicated in autism and brain disorders

[1] Darnell JC(2011)FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism Cell 146 247-61

[2] Van Driesche SJ(1993)The Fmr-1 protein Is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation Nat Genet 4 335-40

[3] Zhang C(2013)The Genotype-Tissue Expression (GTEx) project Nat Genet 45 580-5

[4] Hung KY(2012)Unraveling the brain regulation of appetite: lessons from genetics Nat Neurosci 15 1343-9

[5] Mele A(2014)Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences Hum Mol Genet 23 5479-91

[6] Fraser CE(2014)The contribution of de novo coding mutations to autism spectrum disorder Nature 515 216-21

[7] Devys D(2014)Bias towards large genes in autism Nature 512 E1-2

[8] Lutz Y(2014)A framework for the interpretation of de novo mutation in human disease Nat Genet 46 944-50

[9] Rouyer N(2014)Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder Nat Genet 46 742-7

[10] Bellocq JP(2012)FMRP targets distinct mRNA sequence elements to regulate protein expression Nature 492 382-6

[1] Darnell JC(2011)FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism Cell 146 247-61

[2] Van Driesche SJ(1993)The Fmr-1 protein Is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation Nat Genet 4 335-40

[3] Zhang C(2013)The Genotype-Tissue Expression (GTEx) project Nat Genet 45 580-5

[4] Hung KY(2012)Unraveling the brain regulation of appetite: lessons from genetics Nat Neurosci 15 1343-9

[5] Mele A(2014)Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences Hum Mol Genet 23 5479-91

[6] Fraser CE(2014)The contribution of de novo coding mutations to autism spectrum disorder Nature 515 216-21

[7] Devys D(2014)Bias towards large genes in autism Nature 512 E1-2

[8] Lutz Y(2014)A framework for the interpretation of de novo mutation in human disease Nat Genet 46 944-50

[9] Rouyer N(2014)Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder Nat Genet 46 742-7

[10] Bellocq JP(2012)FMRP targets distinct mRNA sequence elements to regulate protein expression Nature 492 382-6