Bone mesenchymal stem cell extracellular vesicles delivered miR let-7-5p alleviate endothelial glycocalyx degradation and leakage via targeting ABL2

被引：0
|
作者：
Zhe Li
Yuqing Xu
Shiyue Lu
Yuan Gao
Yuxiao Deng
机构：
[1] Renji Hospital,Department of Critical Care Medicine
[2] School of Medicine,undefined
[3] Shanghai Jiao Tong University,undefined
来源：
Cell Communication and Signaling | / 21卷
关键词：
Endothelial glycocalyx; Mesenchymal stem cells; Extracellular vesicles; ABL2; Let-7;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background Inflammation-related Endothelial vascular leakage (EVL) is associated with poor clinical prognosis. Endothelial glycocalyx (EG) is a novel therapeutic target for EVL. bMSCs (Bone Mesenchymal Stem Cells) are potential therapies for EVL, but the effect of bMSCs on EG has not been investigated.
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