Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons

被引:0
作者
Seo-Hee Ahn
Hee Jung Kim
Imju Jeong
Yi Jae Hong
Myung-Jun Kim
Duck-Joo Rhie
Yang-Hyeok Jo
Sang June Hahn
Shin Hee Yoon
机构
[1] The Catholic University of Korea,Department of Physiology, College of Medicine
[2] The Catholic University of Korea,the Catholic Institute for Advanced Biomaterials
[3] Dankook University,Department of Physiology, College of Medicine
来源
BMC Neuroscience | / 12卷
关键词
Nitric Oxide; Nimodipine; Oxygen Glucose Deprivation; Viable Neuron; Grape Seed Extract;
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[1]  
Fine AM(2000)Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications Altern Med Rev 5 144-151
[2]  
Bagchi D(1998)Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice Gen Pharmacol 30 771-776
[3]  
Garg A(2001)Protection of primary glial cells by grape seed proanthocyanidin extract against nitrosative/oxidative stress Nitric Oxide 5 137-149
[4]  
Krohn RL(2009)Oral administration of grape polyphenol extract ameliorates cerebral ischemia/reperfusion-induced neuronal damage and behavioral deficits in gerbils: comparison of pre- and post-ischemic administration J Nutr Biochem 20 369-377
[5]  
Bagchi M(2002)Protective effects of a novel niacin-bound chromium complex and a grape seed proanthocyanidin extract on advancing age and various aspects of syndrome X Ann N Y Acad Sci 957 250-259
[6]  
Bagchi DJ(2003)Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidation Carcinogenesis 24 1379-1388
[7]  
Balmoori J(1996)Structure-antioxidant activity relationships of flavonoids and phenolic acids Free Radic Biol Med 20 933-956
[8]  
Stohs SJ(1987)Glutamate neurotoxicity in cortical cell culture J Neurosci 7 357-368
[9]  
Roychowdhury S(2010)Glutamate receptors, neurotoxicity and neurodegeneration Pflugers Arch 460 525-542
[10]  
Wolf G(1987)Ionic dependence of glutamate neurotoxicity J Neurosci 7 369-379