BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats

被引：0
作者：
Zhenyu Li
Qingxian Li
Kai Tong
Jiayong Zhu
Hui Wang
Biao Chen
Liaobin Chen
机构：
[1] Zhongnan Hospital of Wuhan University,Division of Joint Surgery and Sports Medicine, Department of Orthopedic Surgery
[2] Wuhan University,Department of Pharmacology, Wuhan University Taikang Medical School (School of Basic Medical Sciences)
[3] Hubei Provincial Key Laboratory of Developmentally Originated Disease,undefined
来源：
Stem Cell Research & Therapy | / 13卷
关键词：
Bone marrow stromal cell; Exosome; Macrophage polarization; Tendon-bone healing; miRNA;
D O I：
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  • [1] Zbrojkiewicz D(2018)Increasing rates of anterior cruciate ligament reconstruction in young Australians, 2000–2015 Med J Aust 208 354-358
  • [2] Vertullo C(2016)Incidence of anterior cruciate ligament tears and reconstruction: a 21-year population-based study Am J Sports Med 44 1502-1507
  • [3] Grayson JE(2007)The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis Am J Sports Med 35 1756-1769
  • [4] Sanders TL(2012)Return-to-sport outcomes at 2 to 7 years after anterior cruciate ligament reconstruction surgery Am J Sports Med 40 41-48
  • [5] Maradit Kremers H(2013)ACL graft healing and biologics Clin Sports Med 32 93-109
  • [6] Bryan AJ(2017)Macrophage Polarization Annu Rev Physiol 79 541-566
  • [7] Larson DR(2005)Macrophages accumulate in the early phase of tendon-bone healing J Orthop Res 23 1425-1432
  • [8] Dahm DL(2011)An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice J Clin Invest 121 985-997
  • [9] Levy BA(2009)Selective and specific macrophage ablation is detrimental to wound healing in mice Am J Pathol 175 2454-2462
  • [10] Lohmander LS(2019)Concise review: mesenchymal stem cells: from roots to boost Stem Cells 37 855-864
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