Estimation of metabolite T1 relaxation times using tissue specific analysis, signal averaging and bootstrapping from magnetic resonance spectroscopic imaging data

被引：0
作者：
H. Ratiney
S. M. Noworolski
M. Sdika
R. Srinivasan
R. G. Henry
S. J. Nelson
D. Pelletier
机构：
[1] University of California,Department of Neurology
[2] University of California,Department of Radiology
来源：
Magnetic Resonance Materials in Physics, Biology and Medicine | 2007年 / 20卷
关键词：
MR spectroscopic imaging; Relaxation time T; estimation; Bootstrap; Monte Carlo simulation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Object A novel method of estimating metabolite T1 relaxation times using MR spectroscopic imaging (MRSI) is proposed. As opposed to conventional single-voxel metabolite T1 estimation methods, this method investigates regional and gray matter (GM)/white matter (WM) differences in metabolite T1 by taking advantage of the spatial distribution information provided by MRSI.
引用
收藏
页码：143 / 155
页数：12
相关论文
共 109 条
[1]  
Brief EE(2003)Proton T1 relaxation times of cerebral metabolites differ within and between regions of normal human brain NMR Biomed 16 503-509
[2]  
Whittall KP(2003)Comparison of longitudinal metabolite relaxation times in different regions of the human brain at 1.5 and 3 Tesla Magn Reson Med 50 1296-1301
[3]  
Li DK(2005)Integrated data acquisition and processing to determine metabolite contents, relaxation times, and macromolecule baseline in single examinations of individual subjects Magn Reson Med 54 761-768
[4]  
MacKay A(2001)Proton T (1) and T (2) relaxation times of human brain metabolites at 3 Tesla NMR Biomed 14 325-331
[5]  
Ethofer T(2002)Relaxation times of choline, creatine and N-acetyl aspartate in human cerebral white matter at 1.5 T NMR Biomed 15 215-221
[6]  
Mader I(2004)1H metabolite relaxation times at 3.0 tesla: measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation J Magn Reson Imaging 19 537-545
[7]  
Seeger U(1994)Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1 T Magn Reson Med 32 565-571
[8]  
Helms G(2006)Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging NMR Biomed 19 492-503
[9]  
Erb M(1999)High spatial resolution 1H-MRSI and segmented MRI of cortical gray matter and subcortical white matter in three regions of the human brain Magn Reson Med 41 21-29
[10]  
Grodd W(2001)Segmentation of brain MR images through a hidden Markov random field model and the expectation maximization algorithm IEEE Trans Med Imaging 20 45-57
12345678910