piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense

被引：0
|
作者：
Allison C Billi
Mallory A Freeberg
John K Kim
机构：
[1] University of Michigan,Life Sciences Institute, Department of Human Genetics
[2] University of Michigan,Department of Human Genetics
[3] University of Michigan,Department of Computational Medicine and Bioinformatics
来源：
Genome Biology | / 13卷
关键词：
piRNA; siRNA; Piwi; germline; genome surveillance; epigenetics; gene silencing; transposable elements;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Caenorhabditis elegans piRNAs promote genome surveillance by triggering siRNA-mediated silencing of nonself DNA in competition with licensing programs that support endogenous gene expression.
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