4-Hydroxy-2-quinolones 113. Synthesis and antitubercular activity of N-R-amides of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8-hexahydroquinoline- 3-carboxylic acid

被引：0

作者：

Ukrainets I.V. ^{[1
]}

Kolesnik E.V. ^{[1
]}

Sidorenko L.V. ^{[1
]}

Gorokhova O.V. ^{[1
]}

Turov A.V. ^{[2
]}

机构：

[1] National Pharmaceutical University

[2] Kiev Taras Shevchenko National University

来源：

Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 03期

关键词：

4-hydroxy-2-oxoquinoline-3-carboxylic acids; Amides; Antitubercular activity; Thermolysis; X-ray structural analysis;

D O I：

10.1007/s10593-007-0049-2

中图分类号：

学科分类号：

摘要：

A preparative method has been developed and the synthesis has been effected of anilides and heterylamides of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8- hexahydroquinoline-3-carboxylic acid. A comparative analysis has been carried out of the structure and antitubercular properties of the synthesized compounds and their analogs unsubstituted in the quinoline nucleus. © 2007 Springer Science+Business Media, Inc.

引用

页码：326 / 333

页数：7

共 50 条

[31] 4-Hydroxy-2-quinolones. 40. Synthesis and biological properties of anilides of 1H-2-oxo-4-hydroxyquinoline-3-carboxylic acid
Ukrainets, I.V.
Taran, S.G.
Gorokhova, O.V.
Taran, E.A.
Jaradat, N.A.
Petukhova, I.Yu.
Chemistry of Heterocyclic Compounds, 2000, 36 (02) : 166 - 169
[32] 4-Hydroxy-2-quinolones 126. 1-Hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1- ij]quinoline-2-carboxylic acid hydrazide and its derivatives
Ukrainets I.V.
Tkach A.A.
Mospanova E.V.
Svechnikova E.N.
Chemistry of Heterocyclic Compounds, 2007, 43 (08) : 1014 - 1019
[33] 4-Hydroxy-2-quinolones. 154*. Pyrimidin- 2-ylamides of 1-r-4-hydroxy-2-oxo-1,2-dihydro- quinoline-3-carboxylic acids. synthesis, structure, and properties
I. V. Ukrainets
A. A. Tkach
L. A. Grinevich
A. V. Turov
O. V. Bevz
Chemistry of Heterocyclic Compounds, 2009, 45 : 567 - 579
[34] 4-hydroxy-2-quinolones. 149*. Synthesis, chemical transformations, and biological properties of β-N-acylhydrazides of 1-R-4-hydroxy-2-oxo-1,2-dihydro-quinoline-4-carboxylic acids
Ukrainets, I. V.
Tkach, A. A.
Yang, Liu Yang
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (11) : 1347 - 1354
[35] 4-hydroxy-2-quinolones. 149*. Synthesis, chemical transformations, and biological properties of β-N-acylhydrazides of 1-R-4-hydroxy-2-oxo-1,2-dihydro-quinoline-4-carboxylic acids
I. V. Ukrainets
A. A. Tkach
Liu Yang Yang
Chemistry of Heterocyclic Compounds, 2008, 44 : 1347 - 1354
[36] 4-Hydroxy-2-quinolones. 180*. Synthesis, chemical reactions, and analgesic activity of 1-allyl-4-hydroxy-6,7-dimethoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid alkylamides
I. V. Ukrainets
E. V. Mospanova
A. A. Davidenko
S. V. Shishkina
Chemistry of Heterocyclic Compounds, 2010, 46 : 1084 - 1095
[37] 4-Hydroxy-2-quinolones. 111. Simple synthesis of 1-substituted 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acids
Ukrainets I.V.
Gorokhova O.V.
Sidorenko L.V.
Bereznyakova N.L.
Chemistry of Heterocyclic Compounds, 2007, 43 (01) : 58 - 62
[38] 4-Hydroxy-2-quinolones 141. Synthesis and structure of 5R-3-hydroxy-1,5-dihydropyrazolo[4,3-c]quinolin-4-ones
I. V. Ukrainets
V. V. Kravtsova
A. A. Tkach
G. Sim
Chemistry of Heterocyclic Compounds, 2008, 44
[39] 4-Hydroxy-2-quinolones 138. Synthesis and study of structure-biological activity relationships in a series of 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3, 2,1-ij]quinoline-2-carboxylic acid anilides
Ukrainets I.V.
Mospanova E.V.
Bereznyakova N.L.
Naboka O.I.
Chemistry of Heterocyclic Compounds, 2007, 43 (12) : 1532 - 1539
[40] 4-HYDROXY-2-QUINOLONES. 180. SYNTHESIS, CHEMICAL REACTIONS, AND ANALGESIC ACTIVITY OF 1-ALLYL-4-HYDROXY-6,7-DIMETHOXY-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ALKYLAMIDES
Ukrainets, I. V.
Mospanova, E. V.
Davidenko, A. A.
Shishkina, S. V.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2010, 46 (09) : 1084 - 1095

← 1 2 3 4 5 →