4-Hydroxy-2-quinolones 113. Synthesis and antitubercular activity of N-R-amides of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8-hexahydroquinoline- 3-carboxylic acid

被引：0

作者：

Ukrainets I.V. ^{[1
]}

Kolesnik E.V. ^{[1
]}

Sidorenko L.V. ^{[1
]}

Gorokhova O.V. ^{[1
]}

Turov A.V. ^{[2
]}

机构：

[1] National Pharmaceutical University

[2] Kiev Taras Shevchenko National University

来源：

Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 03期

关键词：

4-hydroxy-2-oxoquinoline-3-carboxylic acids; Amides; Antitubercular activity; Thermolysis; X-ray structural analysis;

D O I：

10.1007/s10593-007-0049-2

中图分类号：

学科分类号：

摘要：

A preparative method has been developed and the synthesis has been effected of anilides and heterylamides of 4-hydroxy-6-methyl-2-oxo-1-propyl-1,2,5,6,7,8- hexahydroquinoline-3-carboxylic acid. A comparative analysis has been carried out of the structure and antitubercular properties of the synthesized compounds and their analogs unsubstituted in the quinoline nucleus. © 2007 Springer Science+Business Media, Inc.

引用

页码：326 / 333

页数：7

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