Transcriptional control of natural killer cell differentiation and function

被引：0
|
作者：
Alfonso Martín-Fontecha
Graham M. Lord
Hugh J. M. Brady
机构：
[1] King’s College London,Medical Research Council (MRC) Centre for Transplantation, Guy’s Hospital
[2] Imperial College London,Section of Immunity and Infection, Cell and Molecular Biology Division, Department of Life Sciences, Immunology and Infection
来源：
Cellular and Molecular Life Sciences | 2011年 / 68卷
关键词：
Transcription factor; NK cell differentiation; Migration; Effector function;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Gene expression can be modulated depending on physiological and developmental requirements. A multitude of regulatory genes, which are organized in interdependent networks, guide development and eventually generate specific phenotypes. Transcription factors (TF) are a key element in the regulatory cascade controlling cell fate and effector functions. In this review, we discuss recent data on the diversity of TF that determine natural killer (NK) cell fate and NK cell function.
引用
收藏
页码：3495 / 3503
页数：8
相关论文
共 50 条
  • [41] NATURAL-KILLER-CELL SUBSETS - MATURATION, DIFFERENTIATION AND REGULATION
    BONAVIDA, B
    LEBOW, LT
    JEWETT, A
    NATURAL IMMUNITY, 1993, 12 (4-5) : 194 - 208
  • [42] NATURAL-KILLER CELL-DIFFERENTIATION IN HUMAN THYMUS
    HEIKEN, H
    WORDELMANN, K
    UCIECHOWSKI, P
    ZIEMER, G
    SCHMIDT, RE
    IMMUNOBIOLOGY, 1988, 178 (1-2) : 105 - 106
  • [43] Impaired natural killer cell differentiation in myelodysplastic syndromes.
    Kiladjian, JJ
    Bourgeois, E
    Bourhis, JH
    Chouaib, S
    Fenaux, P
    Caignard, A
    BLOOD, 2003, 102 (11) : 917A - 917A
  • [44] Murine natural killer cell differentiation: Past, present, and future
    Moore, TA
    Bennett, M
    Kumar, V
    IMMUNOLOGIC RESEARCH, 1996, 15 (02) : 151 - 162
  • [45] Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function
    Tremblay-McLean, Alexandra
    Coenraads, Sita
    Kiani, Zahra
    Dupuy, Franck P.
    Bernard, Nicole F.
    BMC IMMUNOLOGY, 2019, 20 (1)
  • [46] Structure and function of natural killer cell surface receptors
    Radaev, S
    Sun, PD
    ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2003, 32 : 93 - 114
  • [47] Function and specificity of human natural killer cell receptors
    Moretta, A
    Parolini, S
    Castriconi, R
    Bottino, C
    Vitale, M
    Sivori, S
    Millo, R
    EUROPEAN JOURNAL OF IMMUNOGENETICS, 1997, 24 (06): : 457 - 468
  • [48] Effect of Hydroxychloroquine on Natural Killer Cell Activity and Function
    Elemam, Noha
    Talaat, Iman
    Maghazachi, Azzam
    PHYSIOLOGY, 2023, 38
  • [49] The neuropeptide galanin modulates natural killer cell function
    Koller, Andreas
    Bianchini, Rodolfo
    Schlager, Sandra
    Muenz, Christian
    Kofler, Barbara
    Wiesmayr, Silke
    NEUROPEPTIDES, 2017, 64 : 109 - 115
  • [50] Structure and function of natural-killer-cell receptors
    Sun, PD
    IMMUNOLOGIC RESEARCH, 2003, 27 (2-3) : 539 - 548
12345