Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling

被引：0
|
作者：
Qianxi Yang
Shaorong Zhao
Zhendong Shi
Lixia Cao
Jingjing Liu
Teng Pan
Dongdong Zhou
Jin Zhang
机构：
[1] Tianjin Medical University Cancer Institute and Hospital,Third Department of Breast Surgery
[2] National Clinical Research Center for Cancer,undefined
[3] Key Laboratory of Cancer Prevention and Therapy,undefined
[4] Clinical Research Center for Cancer,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 40卷
关键词：
Chemotherapy-elicited exosomes; miR-378a-3p; miR-378d; Chemotherapy resistance; Cancer stemness;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway
    Xia, Wenjie
    Chen, Wuzhen
    Ni, Chao
    Meng, Xuli
    Wu, Jun
    Yang, Qiong
    Tang, Hongchao
    Yuan, Hongjun
    Fang, Shan
    BREAST CANCER RESEARCH, 2023, 25 (01)
  • [32] Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway
    Wenjie Xia
    Wuzhen Chen
    Chao Ni
    Xuli Meng
    Jun Wu
    Qiong Yang
    Hongchao Tang
    Hongjun Yuan
    Shan Fang
    Breast Cancer Research, 25
  • [33] Salidroside Inhibits Ischemia/Reperfusion-Induced Myocardial Apoptosis by Targeting Mir-378a-3p Via the Igf1r/Pi3k/Akt Signaling Pathway
    Yan, Tingxu
    Li, Xu
    Nian, Tingting
    Zhang, Xiaozhuo
    He, Bosai
    Bi, Kaishun
    Wang, Zhenzhong
    TRANSPLANTATION PROCEEDINGS, 2022, 54 (07) : 1970 - 1983
  • [34] EZH2 inhibition suppresses bladder cancer cell growth and metastasis via the JAK2/STAT3 signaling pathway
    Chen, Zhiyuan
    Du, Yang
    Liu, Xiuheng
    Chen, Hui
    Weng, Xiaodong
    Guo, Jia
    Wang, Min
    Wang, Xiao
    Wang, Lei
    ONCOLOGY LETTERS, 2019, 18 (01) : 907 - 915
  • [35] DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma
    Zhu, Bin
    Chen, Jun-Jie
    Feng, Ying
    Yang, Jun-Ling
    Huang, Hua
    Chung, Wen Yuan
    Hu, Yi-Lin
    Xue, Wan-Jiang
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2021, 40 (01)
  • [36] Exosomal PD-L1 confers chemoresistance and promotes tumorigenic properties in esophageal cancer cells via upregulating STAT3/miR-21
    Haojie Wang
    Yijun Qi
    Zijun Lan
    Qiwei Liu
    Juanjuan Xu
    Mengxi Zhu
    Tingting Yang
    Ruolin Shi
    Shegan Gao
    Gaofeng Liang
    Gene Therapy, 2023, 30 : 88 - 100
  • [37] Exosomal PD-L1 confers chemoresistance and promotes tumorigenic properties in esophageal cancer cells via upregulating STAT3/miR-21
    Wang, Haojie
    Qi, Yijun
    Lan, Zijun
    Liu, Qiwei
    Xu, Juanjuan
    Zhu, Mengxi
    Yang, Tingting
    Shi, Ruolin
    Gao, Shegan
    Liang, Gaofeng
    GENE THERAPY, 2023, 30 (1-2) : 88 - 100
  • [38] MiR-375 inhibits the sternness of breast cancer cells by blocking the JAK2/STAT3 signaling
    Zhao, Qiong
    Liu, Yichen
    Wang, Ting
    Yang, Yue
    Ni, Haiwei
    Liu, Hai
    Guo, Qianqian
    Xi, Tao
    Zheng, Lufeng
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2020, 884
  • [39] The SP1-Induced Long Noncoding RNA, LINC00339, Promotes Tumorigenesis in Colorectal Cancer via the miR-378a-3p/MED19 Axis
    Ye, Hua
    Li, Wende
    W, Kefeng
    Liu, Yi
    Lv, Yingnian
    Zhu, Yuzhen
    Luo, Hui
    Cui, Liao
    ONCOTARGETS AND THERAPY, 2020, 13 : 11711 - 11724
  • [40] LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling
    Jie Luo
    Keliang Wang
    Shuyuan Yeh
    Yin Sun
    Liang Liang
    Yao Xiao
    Wanhai Xu
    Yuanjie Niu
    Liang Cheng
    Sankar N. Maity
    Runze Jiang
    Chawnshang Chang
    Nature Communications, 10
12345