Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling

被引:0
|
作者
Qianxi Yang
Shaorong Zhao
Zhendong Shi
Lixia Cao
Jingjing Liu
Teng Pan
Dongdong Zhou
Jin Zhang
机构
[1] Tianjin Medical University Cancer Institute and Hospital,Third Department of Breast Surgery
[2] National Clinical Research Center for Cancer,undefined
[3] Key Laboratory of Cancer Prevention and Therapy,undefined
[4] Clinical Research Center for Cancer,undefined
关键词
Chemotherapy-elicited exosomes; miR-378a-3p; miR-378d; Chemotherapy resistance; Cancer stemness;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] A LHFPL3-AS1/miR-580-3p/STAT3 Feedback Loop Promotes the Malignancy in Melanoma via Activation of JAK2/STAT3 Signaling
    Peng, Qian
    Liu, Linbo
    Pei, Hui
    Zhang, Jianwen
    Chen, Minjing
    Zhai, Xiaomei
    MOLECULAR CANCER RESEARCH, 2020, 18 (11) : 1724 - 1734
  • [22] The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling
    Liu, Yi-Ping
    Heng, Jin-Yu
    Zhao, Xin-Yu
    Li, En-You
    JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 19 (01)
  • [23] The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling
    Yi-Ping Liu
    Jin-Yu Heng
    Xin-Yu Zhao
    En-You Li
    Journal of Translational Medicine, 19
  • [24] MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2
    Xinxin Xu
    Yang Li
    Guoxiao Liu
    Kai Li
    Peng Chen
    Yunhe Gao
    Wenquan Liang
    Hongqing Xi
    Xinxin Wang
    Bo Wei
    Hongtao Li
    Lin Chen
    Cancer Biology & Medicine, 2022, 19 (12) : 1662 - 1682
  • [25] MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2
    Xinxin Xu
    Yang Li
    Guoxiao Liu
    Kai Li
    Peng Chen
    Yunhe Gao
    Wenquan Liang
    Hongqing Xi
    Xinxin Wang
    Bo Wei
    Hongtao Li
    Lin Chen
    Cancer Biology & Medicine, 2022, (12) : 1662 - 1682
  • [26] MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2
    Xu, Xinxin
    Li, Yang
    Liu, Guoxiao
    Li, Kai
    Chen, Peng
    Gao, Yunhe
    Liang, Wenquan
    Xi, Hongqing
    Wang, Xinxin
    Wei, Bo
    Li, Hongtao
    Chen, Lin
    CANCER BIOLOGY & MEDICINE, 2022, 19 (12) : 1662 - 1682
  • [27] Loss of lncRNA-SNHG7 Promotes the Suppression of Hepatic Stellate Cell Activation via miR-378a-3p and DVL2 (vol 17, pg 235, 2019)
    Yu, Fujun
    Dong, Peihong
    Mao, Yefan
    Zhao, Binyu
    Huang, Zhiming
    Zheng, Jianjian
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2021, 23 : 215 - 216
  • [28] Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer
    Peixin Du
    Hao Zeng
    Yinan Xiao
    Yunuo Zhao
    Bo Zheng
    Yaotiao Deng
    Jie Liu
    Boyan Huang
    Xinyao Zhang
    Keyi Yang
    Yu Jiang
    Xuelei Ma
    Cell Death & Disease, 11
  • [29] Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer
    Du, Peixin
    Zeng, Hao
    Xiao, Yinan
    Zhao, Yunuo
    Zheng, Bo
    Deng, Yaotiao
    Liu, Jie
    Huang, Boyan
    Zhang, Xinyao
    Yang, Keyi
    Jiang, Yu
    Ma, Xuelei
    CELL DEATH & DISEASE, 2020, 11 (09)
  • [30] DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma
    Bin Zhu
    Jun-Jie Chen
    Ying Feng
    Jun-Ling Yang
    Hua Huang
    Wen Yuan Chung
    Yi-Lin Hu
    Wan-Jiang Xue
    Journal of Experimental & Clinical Cancer Research, 40