Decumbenone C, a new cytotoxic decaline derivative from the marine fungus Aspergillus sulphureus KMM 4640

被引:0
|
作者
Olesya I. Zhuravleva
Shamil Sh. Afiyatullov
Olesya S. Vishchuk
Vladimir A. Denisenko
Natalya N. Slinkina
Olga F. Smetanina
机构
[1] Far Eastern Federal University,G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch
[2] Russian Academy of Sciences,undefined
来源
Archives of Pharmacal Research | 2012年 / 35卷
关键词
Decumbenones; Cytotoxic activity;
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中图分类号
学科分类号
摘要
A new decaline derivative, decumbenone C (1) along with four known compounds, decumbenones A (2) and B (3), diorcinol (4), and brevianamide F (5) were isolated from the marine fungus Aspergillus sulphureus KMM 4640. Decumbenone C shows potent cytotoxic activity against SK-MEL-5 human melanoma cells with IC50 values of 0.9 μM.
引用
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页码:1757 / 1762
页数:5
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