Study of genotoxicity and antigenotoxicity of the Cotinus coggygria Scop. methanol extract by Drosophila melanogaster sex-linked recessive lethal test

被引：0
|
作者：
S. Stanić
S. Matić
G. Đelić
M. Mihailović
D. Bogojević
S. Solujić
机构：
[1] University of Kragujevac,Department of Biology and Ecology, Faculty of Science
[2] University of Belgrade,Department of Molecular Biology, Institute for Biological Research
[3] University of Kragujevac,Department of Chemistry, Faculty of Science
来源：
Russian Journal of Genetics | 2011年 / 47卷
关键词：
Gallic Acid; Methanol Extract; Oleu Ropein; Ethyl Methane Sulfonate; Methyl Gallate;
D O I：
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摘要：
The genotoxic and antigenotoxic effects of Cotinus coggygria Scop. methanol extract was investigated using the Drosophila sex-linked recessive lethal (or SLRL) test. The results presented here show that the methanol extract of Cotinus coggygria in a concentration of 5% and artificial chemical agent ethyl methanesulfonate EMS (0.75 ppm) induce recessive lethal mutations on X-chromosome on Drosophila melanogaster in all broods (I, II and III). Post-treatment with lower concentration of the methanol extract of Cotinus coggygria (2%) was effective in reducing genotoxicity of mutagen.
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页码：770 / 774
页数：4
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