Biotechnological production of pyruvic acid

被引：153

作者：

Y. Li

J. Chen

S.-Y. Lun

机构：

[1] Key Laboratory of Industrial Biotechnology,

[2] Ministry of Education,undefined

[3] Southern Yangtze University,undefined

[4] Huihe Road,undefined

[5] No. 170,undefined

[6] Wuxi,undefined

[7] 214036,undefined

[8] P.R. China,undefined

来源：

Applied Microbiology and Biotechnology | 2001年 / 57卷 / 4期

关键词：

Pyruvate; Organic Acid; Chemical Method; Commercial Production; Yeast Strain;

D O I：

10.1007/s002530100804

中图分类号：

学科分类号：

摘要：

Pyruvic acid is an important organic acid widely used in the chemical and drug, as well as agrochemical, industries. Compared with the chemical method, biotechnological production of pyruvic acid is an alternative approach because of the low cost. An overview of biotechnological production of pyruvate, including direct fermentative production employing eukaryotic and prokaryotic microorganisms, production by a resting cell method and an enzymatic method as well as the recovery of pyruvate, is discussed. A multi-vitamin auxotrophic yeast strain, Torulopsis glabrata, has been used in the commercial production of pyruvate; emphasis is therefore placed on the mechanism and characteristics of pyruvate production by this strain.

引用

页码：451 / 459

页数：8