Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

被引：0

作者：

Jae-Hoon Chang

Yichuan Xiao

Hongbo Hu

Jin Jin

Jiayi Yu

Xiaofei Zhou

Xuefeng Wu

Howard M Johnson

Shizuo Akira

Manolis Pasparakis

Xuhong Cheng

Shao-Cong Sun

机构：

[1] The University of Texas MD Anderson Cancer Center,Department of Immunology

[2] University of Florida,Department of Microbiology and Cell Science

[3] Laboratory of Host Defense,undefined

[4] World Premier International Immunology Frontier Research Center,undefined

[5] Osaka University,undefined

[6] Institute for Genetics,undefined

[7] Center for Molecular Medicine,undefined

[8] and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases,undefined

[9] University of Cologne,undefined

[10] The University of Texas Graduate School of Biomedical Sciences,undefined

[11] Present address: Laboratory of Gene Regulation and Signal Transduction,undefined

[12] Department of Pharmacology,undefined

[13] School of Medicine,undefined

[14] University of California at San Diego,undefined

[15] La Jolla,undefined

[16] California,undefined

[17] USA.,undefined

来源：

Nature Immunology | 2012年 / 13卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The processes that underlie maintenance of the identity of regulatory T cells are unclear. Sun and colleagues show that expression of the ubiquitin-conjugating enzyme Ubc13 by these cells is critical for this process.

引用

页码：481 / 490

页数：9

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