1H, 13C and 15N chemical shift assignments of IPSEΔNLS

被引：0
作者：
N. Helge Meyer
Gabriele Schramm
Michael Sattler
机构：
[1] Institute of Structural Biology,Department Chemie, Biomolecular NMR and Center for Integrated Protein Science Munich (CiPSM)
[2] Helmholtz Zentrum München,Cellular Allergology
[3] Technische Universität München,undefined
[4] Research Center Borstel,undefined
来源：
Biomolecular NMR Assignments | 2011年 / 5卷
关键词：
NMR; IgE;
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摘要：
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) is a major immunogenic component of schistosomes. It potently triggers the release of interleukin-4 from basophilic granulocytes in an IgE-dependent manner, suggesting a key function in the modulation of the host’s immune response to Schistosoma mansoni infection. Here we present the near complete assignment of an IPSE/alpha-1 variant, IPSEΔNLS, which comprises the core domain of the protein.
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