Histopathologic and electron microscopic characterization of cutaneous leishmaniasis in Tatera indica and Gerbillus spp. infected with Leishmania major

被引：0
作者：
Oryan A. [1 ]
Mehrabani D. [1 ,2 ]
Owji S.M. [3 ]
Motazedian M.-H. [4 ]
Asgari Q. [4 ]
机构：
[1] Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz
[2] Gastroenterohepatology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz
[3] Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz
[4] Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz
来源：
Comparative Clinical Pathology | 2007年 / 16卷 / 4期
关键词：
Cutaneous leishmaniasis; Electron microscopy; Isoenzyme; Leishmania major; Light microscopy; Morphology; PCR; Rodents; Southern Iran;
D O I：
10.1007/s00580-007-0693-z
中图分类号：
学科分类号：
摘要：
Cutaneous leishmaniasis (CL) is a zoonotic disease transmitted between rodents and canines, mainly by Phlebotomus sand flies and man. In southern Iran, the incidence of this protozoan disease has doubled over the last decade. The present study deals with histopathological features of CL in Tatera indica and Gerbillus spp. that participate in the epidemiology of CL in southern Iran. Thirty-two trapped rodents were evaluated for any Leishmania infection using enzyme electrophoresis and polymerase chain reaction and were concomitantly studied for any histopathological changes. Histopathological studies showed that bone marrow was the tissue of choice for light and electron microscopic study of Leishmania, demonstrating the macrophages infected with the amastigote form of the parasite. This is the first report of the histopathological detection of L. major in naturally infected T. indica and Gerbillus spp in the Larestan region. © Springer-Verlag London Limited 2007.
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页码：275 / 279
页数：4
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