Is There a Place for Dietary Fiber Supplements in Weight Management?

被引:17
作者
Lyon M.R. [1 ,2 ]
Kacinik V. [1 ]
机构
[1] Canadian Center for Functional Medicine, Coquitlam, BC, V3K 6Y2
[2] Food, Nutrition and Health Program, University of British Columbia, Coquitlam, BC, V3K 6Y2
关键词
Appetite regulation; Bile acid receptors; CCK; Dietary fiber; Free fatty acid receptors; GLP-1; Glycemic index; L-cells; Obesity; Oxyntomodulin; PYY;
D O I
10.1007/s13679-012-0016-9
中图分类号
学科分类号
摘要
Inadequate dietary fiber intake is common in modern diets, especially in children. Epidemiological and experimental evidence point to a significant association between a lack of fiber intake and ischemic heart disease, stroke atherosclerosis, type 2 diabetes, overweight and obesity, insulin resistance, hypertension, dyslipidemia, as well as gastrointestinal disorders such as diverticulosis, irritable bowel disease, colon cancer, and cholelithiasis. The physiological effects of fiber relate to the physical properties of volume, viscosity, and water-holding capacity that the fiber imparts to food leading to important influences over the energy density of food. Beyond these physical properties, fiber directly impacts a complex array of microbiological, biochemical, and neurohormonal effects directly through modification of the kinetics of digestion and through its metabolism into constituents such as short chain fatty acids, which are both energy substrates and important enteroendocrine ligands. Of particular interest to clinicians is the important role dietary fiber plays in glucoregulation, appetite, and satiety. Supplementation of the diet with highly functional fibers may prove to play an important role in long-term obesity management. © 2012 The Author(s).
引用
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页码:59 / 67
页数:8
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