An Update on the Management of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)

被引:0
作者
Taymeyah Al-Toubah
Simona Grozinsky-Glasberg
Jonathan Strosberg
机构
[1] Moffitt Cancer Center,Department of GI Oncology
[2] Hadassah-Hebrew University Medical Center,Neuroendocrine Tumor Unit, ENETS Center of Excellence, Department of Endocrinology and Metabolism
来源
Current Treatment Options in Oncology | 2021年 / 22卷
关键词
Diffuse Pulmonary Neuroendocrine Cell Hyperplasia; DIPNECH; Management; Somatostatin analogs;
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摘要
DIPNECH is caused by an idiopathic proliferation of pulmonary neuroendocrine cells which can lead to bronchiolitis and multifocal lung neuroendocrine tumors. Patients often present with chronic cough and dyspnea. Larger NETs may develop malignant potential. Somatostatin analogs can palliate chronic symptoms, particularly cough. Surgical resection can be considered for relatively large (e.g. >1 cm), progressive tumors.
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