Effects of transcutaneous electrical spinal cord stimulation on stepping patterns during walking

被引:0
作者
Bogacheva I.N. [1 ]
Moshonkina T.R. [1 ]
Savokhin A.A. [1 ]
Shcherbakova N.A. [1 ]
Gladchenko D.A. [2 ]
Gorodnichev R.M. [2 ]
Gerasimenko Y.P. [1 ]
机构
[1] Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg
[2] Velikie Luki State Academy of Physical Education and Sports, Velikie Luki
基金
俄罗斯基础研究基金会;
关键词
spinal cord; stepping pattern; transcutaneous electrical stimulation;
D O I
10.1134/S0362119717050036
中图分类号
学科分类号
摘要
Effects of transcutaneous electrical spinal cord stimulation (tESCS) on the parameters of stepping movements in healthy subjects were investigated during two kinds of activity: walking on a moving treadmill belt (active treadmill) as well as pushing the treadmill belt by effort of the legs (passive treadmill). It was found that the total interference electromyogram (EMG) activity during stepping performance on a passive treadmill was 1.5–2 times higher than during stepping on an active treadmill. In addition, the amplitude of angular displacement of the hip joint and ankle was 2.5 times and 1.7 times higher, respectively, during passive vs. active treadmill, while the duration of stepping cycle decreased by 19%. Although the muscles were exposed to different load and the parameters of motion on the active and passive treadmill were different, tESCS caused an increase in the total EMG activity in 96% of cases both on the active and on the passive treadmill. In both cases, the stepping cycle period decreased by 4–43% in all subjects. These results suggest that tESCS can affect voluntary stepping patterns under conditions of different afferent control. © 2017, Pleiades Publishing, Inc.
引用
收藏
页码:512 / 517
页数:5
相关论文
共 22 条
[1]  
Dimitrijevic M., Gerasimenko Y., Pinter M., Evidence for a spinal central pattern generator in humans, Ann. N.Y. Acad. Sci., 860, (1998)
[2]  
Minassian K., Persy I., Rattay F., Et al., Human lumbar cord circuitries can be activated by extrinsic tonic input to generate locomotor like activity, Hum. Mov. Sci., 26, (2007)
[3]  
Harkema S., Gerasimenko Y., Hodes J., Et al., Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study, Lancet, 377, (2011)
[4]  
Angeli C.A., Edgerton V.R., Gerasimenko Y.P., Harkema S.J., Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans, Brain, 137, 5, (2014)
[5]  
Moshonkina T.R., Bogacheva I.N., Scherbakova N.A., Et al., Electric stimulation of the spinal cord is an effective method to regulate the locomotor functions, in Neirodegenerativnye zabolevaniya: ot genoma do tselostnogo organizma (Neurodegenerative Diseases: From the Genome to the Whole Organism), 1, (2014)
[6]  
Musienko P.E., Bogacheva I.N., Savokhin A.A., Kilimnik V.A., Gorskii O.V., Nikitin O.A., Gerasimenko Y.P., Initiation of locomotor activity in decerebrate and spinal cats using noninvasive transcutaneous electrical stimulation of the spinal cord, Neurosci. Behav. Physiol., 45, 5, pp. 505-511, (2015)
[7]  
Gorodnichev R.M., Pivovarova E.A., Pukhov A., Et al., Transcutaneous electrical stimulation of the spinal cord: a noninvasive method to activate the human pacing movement generators, Fiziol. Chel., 38, 2, (2012)
[8]  
Gerasimenko Y.P., Lu D.C., Modaber M., Et al., Noninvasive reactivation of motor descending control after paralysis, J. Neurotrauma, (2015)
[9]  
Hofstoetter U.S., Krenn M., Danner S.M., Et al., Augmentation of voluntary locomotor activity by transcutaneous spinal cord stimulation in motor incomplete spinal cord injured individuals, Artif. Organs, 39, 10, (2015)
[10]  
Tsetlin M.L., Issledovaniya po terii avtomatov i modelirovaniyu biologicheskikh sistem (The Theory of Automates and Modeling of Biological Systems), (1969)