Epidemiology of HBV in Pregnant Women, South West Nigeria

被引:0
|
作者
Glory Atilola
Obadara Tomisin
Mayowa Randle
Komolafe O. Isaac
Gbenga Odutolu
Josephine Olomu
Laide Adenuga
机构
[1] Redeemers University,Department of Biological Sciences
[2] Northumbria University,Department of Mathematics and Statistics
[3] Redeemed AIDS Program Action Committee,undefined
来源
Journal of Epidemiology and Global Health | 2018年 / 8卷
关键词
HBV; epidemiology; pregnant women; south-West; Nigeria;
D O I
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学科分类号
摘要
Hepatitis B virus (HBV) remains a leading cause of chronic hepatitis, maternal complications, and neonatal deaths in sub-Saharan Africa. Pregnant women serve as a major reservoir for the persistence and ongoing transmission of hepatitis B virus and HIV in a generalized heterosexual epidemic. The aim of this study is to assess the epidemiology of Hepatitis B infection among pregnant women in South West-Nigeria. This is a cross-sectional study of 353 pregnant women across 10 health facilities in the region. Results showed that of the 353 pregnant women tested, 37 were positive for the HBV antigen giving a prevalence estimate of 10.5% (95% CI: 7.5%–14.2%). We found significant negative association between odds of HBV infection and knowledge of HBV transmission through sex (OR: 0.30: 95%CI–0.11–0.82) and a positive association with blood transfusion in the past three months (OR: 9.5: 95% CI-1.58–57.14). Findings strongly suggest high endemicity of HBV and the possible implication of blood transfusion as a major route of ongoing HBV transmission among pregnant women in south-western Nigeria. We recommend further study of a prospective design to investigate the possible causal link between blood transfusion and the risk of HBV infection among pregnant women in Nigeria.
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页码:115 / 123
页数:8
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