Non-genetic expression of adolescent idiopathic scoliosis: a case report and review of the literature

被引：0
作者：
Joris P. S. Hermus
Lodewijk W. van Rhijn
André van Ooij
机构：
[1] University Hospital Maastricht,Department of Orthopaedic Surgery
来源：
European Spine Journal | 2007年 / 16卷
关键词：
Idiopathic scoliosis; Monozygotic twins; Environmental;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Treating children with idiopathic scoliosis can amaze someone at the many different ways in which the deformity can present. Most authors state that genetics stipulates the course of adolescent idiopathic scoliosis. This is mainly based on the high concordance in monozygotic twins. However, there is indication that environmental factors have influences on adolescent idiopathic scoliosis. This is the first report in which a monozygotic twin pair is described concordant for idiopathic scoliosis but with different apical levels, magnitudes and age at detection of scoliosis which stresses the importance of environmental factors.
引用
收藏
页码：338 / 341
页数：3
相关论文
共 69 条
  • [1] Carr AJ(1990)Adolescent idiopathic scoliosis in identical twins J Bone Joint Surg Br 72 621-625
  • [2] Carr WA(1980)Treatment of idiopathic scoliosis in the Milwaukee brace J Bone Joint Surg Am 62 599-612
  • [3] Moe JH(2006)Chromatin and epigenetics in development: blending cellular memory with cell fate plasticity Development 133 2089-2094
  • [4] Winter RB(1967)Idiopathic scoliosis: genetic and environmental aspects J Med Genet 4 251-257
  • [5] Cavalli G(1986)The Boston bracing system for idiopathic scoliosis. Follow-up results in 295 patients Spine 11 792-801
  • [6] De George FV(1967)A twin study of idiopathic scoliosis Clin Orthop 55 117-126
  • [7] Fisher RL(2005)Epigenetic differences arise during the lifetime of monozygoyic twins Proc Natl Acad Sci USA 102 10604-10609
  • [8] Emans JB(1875)The history of twins, as a criterion of the relative power of nature and nurture Pop Sci Mon 8 345-47
  • [9] Kaelin A(2001)Adolescent idiopathic scoliosis: the effect of brace treatment and the incidence of surgery Spine 26 42-217
  • [10] Bancel P(1998)Idiopathic scoliosis in twins studied by DNA finger printing: the incidence and type scoliosis J Bone Joint Surg Br 80B 212-2005
1234567