Cutaneous leishmaniasis in French Guiana: Revising epidemiology with PCR-RFLP

被引：38
作者：
Simon S. [1 ,3 ]
Nacher M. [1 ,2 ]
Carme B. [1 ,3 ]
Basurko C. [2 ]
Roger A. [2 ]
Adenis A. [2 ]
Ginouves M. [1 ,3 ]
Demar M. [1 ,3 ]
Couppie P. [1 ,3 ,4 ]
机构：
[1] Université de la Guyane, Equipe EA3593 Ecosystemes Amazoniens et Pathologie Tropicale, Campus Saint Denis, Avenue d'Estrées, Cayenne
[2] Cayenne General Hospital, Centre d'Investigation Clinique Epidémiologie Clinique Antilles Guyane CIC CIE 1424, Cayenne
[3] Cayenne General Hospital, Laboratoire Associé - Centre National de Référence Leishmania, Laboratoire Hospito-Universitaire de Parasitologie Mycologie, Cayenne
[4] Cayenne General Hospital, Department of Dermatology, Cayenne, French Guiana
来源：
Tropical Medicine and Health | / 45卷 / 1期
关键词：
Cutaneous leishmaniasis; Epidemiology; French Guiana; Leishmania braziliensis; PCR-RFLP;
D O I：
10.1186/s41182-017-0045-x
中图分类号：
学科分类号：
摘要：
Background: The development of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique for species identification among patients presenting leishmaniasis allowed to better determine the main circulating species in French Guiana. Methods: A descriptive study of the Leishmania species was identified, and their spatiotemporal distribution was conducted using patient records between 2006 and 2013, with 1017 new cases of leishmaniasis diagnosed. Identification was realized by PCR-RFLP on 745 cases. Results: The average proportions for different species were 86.2% for Leishmania (Vianna) guyanensis; 9.7% for Leishmania (Vianna) braziliensis; 2.8% for Leishmania (Leishmania) amazonensis; and 1.3% for Leishmania (Vianna) lainsoni, and no case of Leishmania (Vianna) naiffi was identified. Over this period, the proportion of cases due to L. (V.) braziliensis seemed to increase from 8.9% in 2006 to 13.0% in 2013 notably near the gold mining zones. Conclusions: The use of molecular tools has transformed the view of the local epidemiology of cutaneous leishmaniasis in French Guiana. © 2017 The Author(s).
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  • [1] Neglected tropical diseases, (2017)
  • [2] Desjeux P., Worldwide increasing risk factors for leishmaniasis, Med Microbiol Immunol, 190, 1-2, pp. 77-79, (2001)
  • [3] Desjeux P., Leishmaniasis: current situation and new perspectives, Comp Immunol Microbiol Infect Dis, 27, 5, pp. 305-318, (2004)
  • [4] Alvar J., Velez I.D., Bern C., Herrero M., Desjeux P., Cano J., Jannin J., Boer M., WHO leishmaniasis control team. Leishmaniasis worldwide and global estimates of its incidence, PLoS One, 7, 5, (2012)
  • [5] Floch H., Notes and discussions on forest leishmaniasis in French Guiana, Archives de l'Institut Pasteur de la Guyane Française et de l'Inini, 15, 330, pp. 1-8, (1954)
  • [6] Carme B., Aznar C., Pradinaud R., Absence of a proven resurgence of Chagas disease or cutaneous leishmaniasis in French Guiana over the last two decades, Ann Trop Med Parasitol, 95, 6, pp. 623-625, (2001)
  • [7] Dedet J.P., Cutaneous leishmaniasis in French Guiana: a review, Am J Trop Med Hyg, 43, 1, pp. 25-28, (1990)
  • [8] Dedet J.P., Carme B., Desbois N., Bourdoiseau G., Lachaud L., Pratlong F., Epidemiology of autochthonous leishmaniases in France, Presse Med, 42, 11, pp. 1469-1481, (2013)
  • [9] Basset D., Pratlong F., Ravel C., Puechberty Y.J., Dereure J., Dedet J., P. Les leishmanioses déclarées en France en 1999, Bull Epidemiol Hebd, 5, pp. 19-21, (2001)
  • [10] Rotureau B., Ecology of the leishmania species in the Guianan ecoregion complex, Am J Trop Med Hyg, 74, 1, pp. 81-96, (2006)
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