Curcumin synergistically augments bcr/abl phosphorothioate antisense oligonucleotides to inhibit growth of chronic myelogenous leukemia cells

[1] Ben-Neriah Y(1986)The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. Science 233 212-4

[2] Daley GQ(1985)Structural organization of the bcr gene and its role in the Ph1 translocation. Nature 315 758-61

[3] Mes-Masson AM(2000)The molecular biology of chronic myeloid leukemia. Blood 96 3343-56

[4] Witte ON(1999)Molecular pathogenesis of chronic myeloid leukemia: implications for new therapeutic strategies. Ann Hematol 78 49-64

[5] Baltimore D(2005)15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins. Blood 105 1750-8

[6] Heisterkamp N(2001)Cotreatment with STI-571 Enhances tumor necrosis factor α-related apoptosis-inducing ligand (TRAIL or Apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells. Clin Cancer Res 7 350-7

[7] Stam K(2001)Novel therapies for chronic myelogeous leukemia. Exp Hematol 29 543-56

[8] Groffen J(2002)Antigene effect in K562 cells of a PEG-conjugated triplexforming oligonucleotide targeted to the bcr/abl oncogene. Biochemistry 41 502-10

[9] Groffen J(2003)Anticancer potential of curcuma: preclinical and clinical studies. Anticancer Res 23 363-98

[10] de Klein A(2003)Inhibitory effect of curcumin on proliferation of K562 cells involves down-regulation of P210 Acta Pharmacol Sin 24 1155-60

[1] Ben-Neriah Y(1986)The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. Science 233 212-4

[2] Daley GQ(1985)Structural organization of the bcr gene and its role in the Ph1 translocation. Nature 315 758-61

[3] Mes-Masson AM(2000)The molecular biology of chronic myeloid leukemia. Blood 96 3343-56

[4] Witte ON(1999)Molecular pathogenesis of chronic myeloid leukemia: implications for new therapeutic strategies. Ann Hematol 78 49-64

[5] Baltimore D(2005)15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins. Blood 105 1750-8

[6] Heisterkamp N(2001)Cotreatment with STI-571 Enhances tumor necrosis factor α-related apoptosis-inducing ligand (TRAIL or Apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells. Clin Cancer Res 7 350-7

[7] Stam K(2001)Novel therapies for chronic myelogeous leukemia. Exp Hematol 29 543-56

[8] Groffen J(2002)Antigene effect in K562 cells of a PEG-conjugated triplexforming oligonucleotide targeted to the bcr/abl oncogene. Biochemistry 41 502-10

[9] Groffen J(2003)Anticancer potential of curcuma: preclinical and clinical studies. Anticancer Res 23 363-98

[10] de Klein A(2003)Inhibitory effect of curcumin on proliferation of K562 cells involves down-regulation of P210 Acta Pharmacol Sin 24 1155-60