Serotonin syndrome in an orthopaedic patient secondary to linezolid therapy for MRSA infection

被引：7

作者：

McClean, M. ^{[1
,2
]}

Walsh, J. C. ^{[2
]}

Condon, F. ^{[2
]}

机构：

[1] Waterford Reg Hosp, GP Training Dept, Waterford, Ireland

[2] Midwestern Reg Hosp, Limerick, Ireland

来源：

IRISH JOURNAL OF MEDICAL SCIENCE | 2011年 / 180卷 / 01期

关键词：

Serotonin syndrome; MRSA; Linezolid; Orthopaedic; Citalopram; SSRI; Septic arthritis;

D O I：

10.1007/s11845-010-0597-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 67-year-old patient was admitted for incision and drainage of a recurrent methicillin-resistant Staphylococcus aureus (MRSA) hip abscess. Linezolid therapy was initiated postoperatively. Within 48 h the patient developed confusion, agitation, hypertension and acute renal failure. Citalopram was stopped and resolution of symptoms occurred within 48 h of discontinuing the offending agent. The symptoms observed in our patient were consistent with the Sternbach criteria for serotonin syndrome.

引用

页码：285 / 286

页数：2

共 5 条

[1]

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[2]

Tsiodras S., Gold H.S., Sakoulas G., Eliopoulos G.M., Wennersten C., Venkataraman L., Moellering Jr. R.C., Ferraro M.J., Linezolid resistance in a clinical isolate of Staphylococcus aureus, Lancet, 358, 9277, pp. 207-208, (2001)

[3]

Bodner R.A., Lynch T., Lewis L., Et al., Serotonin syndrome, Neurology, 45, pp. 219-223, (1995)

[4]

Lawrence K.R., Adra M., Gillman P.K., Serotonin toxicity associated with the use of linezolid: A review of post-marketing data, Clin. Infect. Dis., 42, pp. 1578-1583, (2006)

[5]

Sternbach H., The serotonin syndrome, Am. J. Psychiatry, 148, pp. 705-707, (1991)

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