Etomidate for intubation of patients who have sepsis or septic shock - where do we go from here?

被引：0

作者：

Donald EG Griesdale

机构：

[1] Vancouver General Hospital,Department of Medicine, Division of Critical Care Medicine

[2] University of British Columbia,Department of Anesthesia, Pharmacology and Therapeutics and Department of Medicine, Division of Critical Care Medicine

[3] Vancouver General Hospital,Vancouver Coastal Health Research Institute

[4] University of British Columbia,undefined

[5] Centre for Clinical Epidemiology and Evaluation,undefined

来源：

Critical Care | / 16卷

关键词：

Septic Shock; Severe Sepsis; Adrenal Insufficiency; Etomidate; Induction Agent;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Etomidate is an intravenous induction agent that is associated with hemodynamic stability during intubation. The agent is therefore attractive for use in critically ill patients who have a high risk of hemodynamic instability during this procedure. However, etomidate causes adrenal suppression, which itself has been associated with increased mortality in critically ill patients. The ongoing debate surrounding use of etomidate is thus centered on the immediate favorable hemodynamic profile versus the long-term risks of adrenal insufficiency, particularly in patients who have severe sepsis or septic shock.

引用

共 50 条

[31] Ventilator Dependence Risk Score for the Prediction of Prolonged Mechanical Ventilation in Patients Who Survive Sepsis/Septic Shock with Respiratory Failure
Chang, Ya-Chun
Huang, Kuo-Tung
Chen, Yu-Mu
Wang, Chin-Chou
Wang, Yi-Hsi
Tseng, Chia-Cheng
Lin, Meng-Chih
Fang, Wen-Feng
SCIENTIFIC REPORTS, 2018, 8
[32] EFFECTIVE ANTIBIOTIC TREATMENT PRESCRIBED BY EMERGENCY PHYSICIANS IN PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT WITH SEVERE SEPSIS OR SEPTIC SHOCK: WHERE IS THE GAP?
Capp, Roberta
Chang, Yuchiao
Brown, David F. M.
JOURNAL OF EMERGENCY MEDICINE, 2011, 41 (06) : 573 - 580
[33] Procalcitonin level as a marker of severe sepsis and septic shock patients who required polymyxin-B immobilized fiber with direct hemoperfusion
T Ikeda
K Ikeda
S Suda
Critical Care, 16 (Suppl 3):
[34] Lactate levels from arterial, central venous and peripheral venous blood in severe sepsis and septic shock patients
M Assuncao
A Nascente
C Guedes
B Mazza
M Jacki
H Fernandes
F Machado
Critical Care, 11 (Suppl 2):
[35] Mortality of oncohematologic patients admitted to the intensive care unit (ICU) who required invasive mechanical ventilation (IMV). do we have to delay intubation?
Corcia Palomo Y.
Knight Asorey T.
Espigado Tocino I.
Martín Villén L.
Gutiérrez Pizarrayo A.
Garnacho Montero J.
Intensive Care Medicine Experimental, 3 (Suppl 1)
[36] Rate of microbiologically proven infections among patients with severe sepsis/septic shock: results from the German prevalence study
F Brunkhorst
F Bloos
K Reinhart
Critical Care, 10 (Suppl 1):
[37] Prognostic Value of Secretoneurin in Patients With Severe Sepsis and Septic Shock: Data From the Albumin Italian Outcome Sepsis Study
Rosjo, Helge
Masson, Serge
Caironi, Pietro
Stridsberg, Mats
Magnoli, Michela
Christensen, Geir
Moise, Gabriella
Urbano, Maria Cristina
Gattinoni, Luciano
Pesenti, Antonio
Latini, Roberto
Omland, Torbjorn
CRITICAL CARE MEDICINE, 2018, 46 (05) : E404 - E410
[38] An increase in red blood cell distribution width from baseline predicts mortality in patients with severe sepsis or septic shock
Chan Ho Kim
Jung Tak Park
Eun Jin Kim
Jae Hyun Han
Ji Suk Han
Jun Yong Choi
Seung Hyeok Han
Tae-Hyun Yoo
Young Sam Kim
Shin Wook Kang
Hyung Jung Oh
Critical Care, 17
[39] Microparticles from septic shock patients contain microRNA and messenger RNA: new players in the pathogenesis of sepsis?
Luciano CP Azevedo
Juliana M Real
João E Bezerra
Flavia R Machado
Reinaldo Salomao
Critical Care, 17 (Suppl 4):
[40] Study of the correlation between central venous oxygen saturation and venous saturation from the antecubital vein in severe sepsis/septic shock patients
K Piyavechviratana
W Tangpradubkiet
Critical Care, 16 (Suppl 1):

← 1 2 3 4 5 →