Etomidate for intubation of patients who have sepsis or septic shock - where do we go from here?

被引：0

作者：

Donald EG Griesdale

机构：

[1] Vancouver General Hospital,Department of Medicine, Division of Critical Care Medicine

[2] University of British Columbia,Department of Anesthesia, Pharmacology and Therapeutics and Department of Medicine, Division of Critical Care Medicine

[3] Vancouver General Hospital,Vancouver Coastal Health Research Institute

[4] University of British Columbia,undefined

[5] Centre for Clinical Epidemiology and Evaluation,undefined

来源：

Critical Care | / 16卷

关键词：

Septic Shock; Severe Sepsis; Adrenal Insufficiency; Etomidate; Induction Agent;

D O I：

暂无

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学科分类号：

摘要：

Etomidate is an intravenous induction agent that is associated with hemodynamic stability during intubation. The agent is therefore attractive for use in critically ill patients who have a high risk of hemodynamic instability during this procedure. However, etomidate causes adrenal suppression, which itself has been associated with increased mortality in critically ill patients. The ongoing debate surrounding use of etomidate is thus centered on the immediate favorable hemodynamic profile versus the long-term risks of adrenal insufficiency, particularly in patients who have severe sepsis or septic shock.

引用

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