Fluorescent acrylamide nanoparticles for boronic acid based sugar sensing — from probes to sensors

被引：0
作者：
Gunter Zenkl
Ingo Klimant
机构：
[1] Institute of Analytical Chemistry and Radiochemistry,Graz University of Technology
来源：
Microchimica Acta | 2009年 / 166卷
关键词：
Stimuli responsive polymers; Nanoparticles; Fluorescence; Glucose sensors; Phenylboronic acid; Swelling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Fluorescent nanoparticles containing covalently bound phenylboronic acids (~ 250 nm in diameter) are presented that respond to carbohydrates by swelling which is detected using fluorescence resonance energy transfer. The nanoparticles are characterized in terms of kinetics, response time and dynamic range. The response of the particles to glucose at pH 7.5 depends on the kind of phenylboronic acid and on ionic strength. The particles were immobilized in hydrogel sensor layers that enable continuous optical sensing of carbohydrates.
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页码：123 / 131
页数：8
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