Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study

被引：19
作者：
Hirsso P. [1 ,2 ]
Rajala U. [1 ]
Laakso M. [1 ,2 ]
Hiltunen L. [1 ,2 ,3 ]
Härkönen P. [1 ,4 ]
Keinänen-Kiukaanniemi S. [1 ,3 ]
机构：
[1] Department of Public Health Science and General Practice, University of Oulu, FIN-90014 Oulu
[2] Unit of General Practice, Oulu University Hospital
[3] Oulu Health Center, FIN-90015 Oulu
[4] Oulu Deaconess Institute, Department of Sports Medicine, Oulu
来源：
Health and Quality of Life Outcomes | / 3卷 / 1期
关键词：
Androgenic alopecia; Hair loss; Health related quality of life; Insulin resistance;
D O I：
10.1186/1477-7525-3-49
中图分类号：
学科分类号：
摘要：
Background: The aim of this study was to assess the possible associations between female androgenetic alopecia (AGA), insulin resistance and health-related quality of life (HRQOL)-linked factors in women. We hypothesized that not only the mental aspects but also certain physical aspect of women's health, such as insulin resistance, have an important role in the determination of HRQOL among women with hair loss. Methods: A population-based cohort of 330 healthy women aged 63 years, who participated in this study in the City of Oulu in Northern Finland, underwent a medical check-up including assessment of hair status on Ludwig's scale. Background data were collected with a standard questionnaire including a validated RAND 36-Item Health Survey (RAND-36) questionnaire. Results: 105 (31%) women with AGA and 225 (69%) controls completed the RAND-36 questionnaire. The women with AGA were more insulin-resistant than the women with normal hair (QUICKI 0.337 vs. 0.346, p = 0.012). Impaired glucose regulation (IGR) was more prevalent among the former than the latter group (39% vs. 25%). The mean RAND-36 scores were significantly lower on the dimensions of physical functioning, role limitation due to physical health and general health, but not on the mental or social dimensions, among the women with AGA compared with the controls. In multivariate logistic regression analyses with the lowest quintiles of the HRQOL dimensions as the dependent variables and AGA, depression, marital status, education and IGR or QUICKI as independent variables, AGA was independently associated with role limitations due to physical health (2.2, 95% CI 1.20-4.05, 2.45 95% CI 1.32-4.55, respectively). Conclusion: In women aged 63 years, AGA was associated with role limitations due to physical health. Furthermore, the prevalence rates of IGR and insulin resistance measured by QUICKI were higher among the women with hair loss than those with normal hair. © 2005 Hirsso et al; licensee BioMed Central Ltd.
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页数：7
相关论文
共 30 条
[1]  
Norwood O.T., Incidence of female androgenetic alopecia (female pattern alopecia), Dermatol. Surg., 27, pp. 53-54, (2001)
[2]  
Cash T.F., Price V.H., Savin R.C., Psychological effects of androgenetic alopecia on women: Comparisons with balding men and with female control subjects, J. Am. Acad. Dermatol., 29, pp. 568-575, (1993)
[3]  
Maffei C., Fossati A., Rinaldi F., Riva E., Personality disorders and psychopathologic symptoms in patients with androgenetic alopecia, Arch. Dermatol., 130, pp. 868-872, (1994)
[4]  
van der Donk J., Passchier J., Knegt-Junk C., van der Wegen-Keijser, Nieboer C., Stolz E., Verhage F., Psychological characteristics of women with androgenetic alopecia: A controlled study, Br. J. Dermatol., 125, pp. 248-252, (1991)
[5]  
van der Donk J., Hunfeld J.A., Passchier J., Knegt-Junk K.J., Nieboer C., Quality of life and maladjustment associated with hair loss in women with alopecia androgenetica, Soc. Sci. Med., 38, pp. 159-163, (1994)
[6]  
Girman C.J., Hartmaier S., Roberts J., Bergfeld W., Waldstreicher J., Patient-perceived importance of negative effects of androgenetic alopecia in women, J. Womens Health Gend. Based Med., 8, pp. 1091-1095, (1999)
[7]  
Budd D., Himmelberger D., Rhodes T., Cash T.E., Girman C.J., The effects of hair loss in European men: A survey in four countries, Eur. J. Dermatol., 10, pp. 122-127, (2000)
[8]  
Schmidt S., Fischer T.W., Chren M.M., Strauss B.M., Elsner P., Strategies of coping and quality of life in women with alopecia, Br. J. Dermatol., 144, pp. 1038-1043, (2001)
[9]  
Schmidt S., Female alopecia: The mediating effect of attachment patterns on changes in subjective health indicators, Br. J. Dermatol., 148, pp. 1205-1211, (2003)
[10]  
Matilainen V., Koskela P., Keinanen-Kiukaanniemi S., Early androgenetic alopecia as a marker of insulin resistance, Lancet, 356, pp. 1165-1166, (2000)
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