Calcitonin

被引：0
作者：
Julienne K. Kirk
Charley Hepfinger
机构：
[1] Wake Forest University School of Medicine,Department of Family and Community Medicine
[2] Medical Center Boulevard,Ambulatory Care Services (ACS) Clinical Pharmacy
[3] Carl T. Hayden Veterans Affairs Medical Center,undefined
来源：
Clinical Reviews in Bone and Mineral Metabolism | 2005年 / 3卷 / 1期
关键词：
Calcitonin; osteoprosis; review; pharmacotherapy; bone mineral density;
D O I：
10.1385/BMM:3:1:039
中图分类号：
学科分类号：
摘要：
Calcitonin is a 32-amino acid polypeptide secreted by the parafollicular cells of the thyroid. Effects on bone include inhibition of osteoclasts, thus preventing bone resorption, as well as increased renal calcium excretion. Salmon calcitonin is often used therapeutically because it is more potent and has a longer duration of action compared with human calcitonin. Calcitonin also possesses analgesic properties. The mechanism of its analgesic effect is unknown but is thought to involve inhibition of prostaglandins and stimulation of β-endorphins.
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页码：39 / 49
页数：10
相关论文
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