Synthesis and Anti-Inflammatory Activity of Novel Calix[4]Arene Derivatives Containing an Ibuprofen Residue

被引：0
作者：
I. A. Kravchenko
E. A. Alekseeva
A. I. Aleksandrova
A. A. Kobernik
机构：
[1] I. I. Mechnikov Odessa National University,A. V. Bogatskii Physicochemical Institute
[2] Ukrainian National Academy of Sciences,undefined
来源：
Pharmaceutical Chemistry Journal | 2015年 / 49卷
关键词：
calix[4]arenes; ibuprofen; anti-inflammatory activity; carrageenan edema;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Novel derivatives based on calix[4]arene and ibuprofen were prepared. Physicochemical analysis methods were used to identify these compounds. Studies of their anti-inflammatory actions in a carrageenan edema model showed that these substances had greater anti-inflammatory effects than ibuprofen.
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页码：163 / 166
页数：3
相关论文
共 20 条
[1]  
Nasonov EL(2003)undefined Rus. Med. Zh. 11 375-378
[2]  
Lazebnik LB(2004)undefined Rus. Med. Zh. 12 844-847
[3]  
Drozdov VN(1998)undefined Rus. Med. Zh. 6 829-831
[4]  
Kolomiets EV(2002)undefined J. Med. 347 2104-2110
[5]  
Grin’ko AV(2002)undefined Hypertension 39 929-934
[6]  
Chan FK(2008)undefined Top. Cur. Chem. 255 65-96
[7]  
Engl N(2007)undefined Top. Cur. Chem. 277 31-38
[8]  
White WB(2005)undefined Zh. Organ. ta Farmats. Khimiyi 3 13-29
[9]  
Kent J(1991)undefined J. Org. Chem. 56 7256-7263
[10]  
Taylor A(undefined)undefined undefined undefined undefined-undefined
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