Single-cell biomedicine: roles of single-cell nuclear elements

被引：0
作者：
Yiming Zeng
Xiangdong Wang
Jiaqiang Zhang
机构：
[1] Henan Provincial People’s Hospital,Department of Anesthesiology and Perioperative Medicine, Center for Clinical Single Cell Biomedicine
[2] People’s Hospital of Zhengzhou University,Centre for Tumor Diagnosis and Therapy, Jinshan Hospital
[3] Fudan University Shanghai Medical College,Department of Pulmonary and Critical Care Medicine, Clinical Center for Molecular Diagnosis and Therapy
[4] The Second Affiliated Hospital of Fujian Medical University,undefined
来源：
Cell Biology and Toxicology | 2020年 / 36卷
关键词：
Single cell; Transcriptional profiles; DNA sequencing; 3D genome; Single-cell biomedicine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Single-cell biomedicine, a new merging discipline of cell biology and medicine to improve the life quality of patients, gains high priority in cell biology and toxicology. Single-cell nuclear elements are specially focused and headlined to understand regulatory mechanisms by which transcriptional factors, DNA elements, and genome organization interact with each other and contribute to the developmental evolution and dynamic formation of genotoxicity. Cell molecular phenomics, clonal genotypes, and structural metamorphoses during the cell cycle at single-cell level provide deep insights to understanding mechanism-based bridges between cell biology and toxicology, between cell sensitive and resistance, and between chronic diseases and cancer.
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页码：1 / 3
页数：2
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