POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia

被引：0

作者：

Andrew J Ramsay

Víctor Quesada

Miguel Foronda

Laura Conde

Alejandra Martínez-Trillos

Neus Villamor

David Rodríguez

Agnieszka Kwarciak

Cecilia Garabaya

Mercedes Gallardo

Mónica López-Guerra

Armando López-Guillermo

Xose S Puente

María A Blasco

Elías Campo

Carlos López-Otín

机构：

[1] Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Universidad de Oviedo,Departamento de Bioquímica y Biología Molecular

[2] Telomeres and Telomerase Group,undefined

[3] Molecular Oncology Program,undefined

[4] Spanish National Cancer Research Centre (CNIO),undefined

[5] Unidad de Hematopatología,undefined

[6] Servicio de Anatomía Patológica,undefined

[7] Hospital Clínic,undefined

[8] Universitat de Barcelona,undefined

[9] Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS),undefined

来源：

Nature Genetics | 2013年 / 45卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Carlos López-Otín and colleagues report recurrent mutations in POT1 in chronic lymphocytic leukemia. This is the first member of the telomeric shelterin complex reported to be mutated in human cancer.

引用

页码：526 / 530

页数：4

共 69 条

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