Predictors of discontinuation, efficacy, and safety of memantine treatment for Alzheimer’s disease: meta-analysis and meta-regression of 18 randomized clinical trials involving 5004 patients

被引:0
作者
Lídia Blanco-Silvente
Dolors Capellà
Josep Garre-Olmo
Joan Vilalta-Franch
Xavier Castells
机构
[1] University of Girona,TransLab Research Group; Department of Medical Sciences
[2] University of Girona,Department of Medical Sciences, Faculty of Medicine
[3] Girona Biomedical Research Institute (IdibGi),undefined
[4] Parc Hospitalari Martí i Julià,undefined
来源
BMC Geriatrics | / 18卷
关键词
Alzheimer’s disease; Memantine; Discontinuation; Efficacy; Meta-analysis; Meta-regression;
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[1]  
Jönsson L(2006)Determinants of costs of care for patients with Alzheimer’s disease Int J Geriatr Psychiatry 21 449-459
[2]  
Eriksdotter Jönhagen M(2017)Disease progression in mild dementia due to Alzheimer disease in an 18-month observational study (GERAS): the impact on costs and caregiver outcomes Dement Geriatr Cogn Disord Extra 7 87-100
[3]  
Kilander L(1995)Noncompetitive NMDA receptor antagonists with fast open-channel blocking kinetics and strong voltage-dependency as potential therapeutic agents for Alzheimer’s dementia Pharmacopsychiatry 28 113-124
[4]  
Jones RW(1995)MK-801, memantine and amantadine show neuroprotective activity in the nucleus basalis magnocellularis Eur J Pharmacol 293 267-270
[5]  
Lebrec J(2015)EFNS-ENS/EAN guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease Eur J Neurol 22 889-898
[6]  
Kahle-Wrobleski K(2017)Trends in the prescription and long-term utilization of antidementia drugs among patients with Alzheimer's disease in Spain: a cohort study using the registry of dementias of Girona Drugs Aging 34 303-310
[7]  
Müller WE(2017)prescription patterns of medications for Alzheimer’s disease in Japan from 2010 to 2015: a descriptive pharmacy claims database study Neurol Ther 6 25-37
[8]  
Mutschler E(2016)Treatment patterns with antidementia drugs in the united sates: Meidcare cohort study J Am Geriatr Soc 64 1540-1548
[9]  
Riederer P(2014)Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study Int Clin Psychopharmacol 29 216-223
[10]  
Wenk GL(2006)Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease N Engl J Med 355 1525-1538