Pharmaceutically active compounds in aqueous environment: recent developments in their fate, occurrence and elimination for efficient water purification

The existence of pharmaceutically active compounds (PhACs) in the water is a major concern for environmentalists due to their deleterious effects on living organisms even at minuscule concentrations. This review focuses on PhACs such as analgesics and anti-inflammatory compounds, which are massively excreted in urine and account for the majority of pharmaceutical pollution. Furthermore, other PhACs such as anti-epileptics, beta-blockers and antibiotics are discussed because they also contribute significantly to pharmaceutical pollution in the aquatic environment. This review is divided into two parts. In the first part, different classes of PhACs and their fate in the wastewater environment are presented. In the second part, recent advances in the removal of PhACs by conventional wastewater treatment plants, including membrane bioreactors (MBRs), activated carbon adsorption and bench-scale studies concerning a broad range of advanced oxidation processes (AOPs) that render practical and appropriate strategies for the complete mineralization and degradation of pharmaceutical drugs, are reviewed. This review indicates that drugs like diclofenac, naproxen, paracetamol and aspirin are removed efficiently by conventional systems. Activated carbon adsorption is suitable for the removal of diclofenac and carbamazepine, whereas AOPs are leading water treatment strategies for the effective removal of reviewed PhACs.