Diagnosing and Treating Food Allergy

被引：2

作者：

Berni Canani R. ^{[1
,2
]}

Nocerino R. ^{[1
]}

Pezzella V. ^{[1
]}

Leone L. ^{[1
]}

Cozzolino T. ^{[1
]}

Aitoro R. ^{[1
]}

Paparo L. ^{[1
]}

Di Costanzo M. ^{[1
]}

Cosenza L. ^{[1
]}

Troncone R. ^{[1
,2
]}

机构：

[1] Food Allergy Unit, Department of Translational Medicine, University of Naples “Federico II”, Via S. Pansini, 5, Naples

[2] European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II”, Via S. Pansini, 5, Naples

来源：

Current Pediatrics Reports | 2013年 / 1卷 / 3期

关键词：

Atopy patch test; Cow’s milk allergy; Elimination diet; Oral food challenge; Probiotics; Skin prick test;

D O I：

10.1007/s40124-013-0027-3

中图分类号：

学科分类号：

摘要：

Food allergy (FA) is defined as an abnormal immunological reaction to food proteins. Over 90 % of FAs in childhood are caused by eight foods: cow’s milk, hen’s egg, soy, peanuts, tree nuts, wheat, fish and shellfish. The diagnostic work up for a child with suspected FA includes detailed medical history, physical examination, FA screening tests and response to elimination diet and to oral food challenge. Sometimes additional diagnostic tools to explore intestinal damage and function could be adopted. Currently, the only treatment for FA relies on strict elimination diets supervised by the nutritionist. Main new therapeutic strategies for FA include allergen-specific (oral, sublingual, epicutaneous, subcutaneous immunotherapy and heat treatment of food) and non-allergen-specific therapies (humanized monoclonal antibodies, anti-IgE and anti-IL5, probiotics). An incorrect diagnosis is likely to result in unnecessary dietary restrictions, which, if prolonged, may adversely affect the child’s nutritional status and growth. © 2013, Springer Science + Business Media New York.

引用

页码：189 / 197

页数：8

共 61 条

[1]

Kuehn B.M., Food allergies becoming more common, JAMA., 300, (2008)

[2]

Bush R.K., Approach to patients with symptoms of food allergy, Am J Med., 121, pp. 376-378, (2008)

[3]

Food Allergy Training Guide for Hospital and Food Service Staff, FAAN, (2006)

[4]

Berni Canani R., Nocerino R., Terrin G., Et al., Hospital admissions for food-induced anaphylaxis in Italian children, Clin Exp Allergy., 42, pp. 1813-1814, (2012)

[5]

Ramesh S., Food allergy. Overview in children, Clin Rev Allerg Immunol., 34, pp. 217-230, (2008)

[6]

Dias R.P., Summerfield A., Khakoo G.A., Food hypersensitivity among Caucasian and non-Caucasian children, Pediatr Allergy Immunol., 19, pp. 86-89, (2008)

[7]

Bohle B., The impact of pollen-related food allergens on pollen allergy, Allergy., 62, pp. 3-10, (2007)

[8]

Ho M.H., Wong W.H., Chang C., . Clinical spectrum of food allergies: A comprehensive review, Clin Rev Allergy Immunol, (2012)

[9]

Berni Canani R., Ruotolo S., Discepolo V., Et al., The diagnosis of food allergy in children, Curr Opin Pediatr, 20, pp. 584-589, (2008)

[10]

Burks A.W., Tang M., Sicherer S., ICON: Food allergy, J Allergy Clin Immunol, 129, pp. 906-920, (2012)

← 1 2 3 4 5 6 7 →