A multi-centre, double-blind, 12-week, randomized, placebo-controlled trial to assess the efficacy of adjunctive N-Acetylcysteine for treatment-resistant PTSD: a study protocol

被引：0
作者：
Alice Maier
Anita Dharan
Gina Oliver
Michael Berk
Suzy Redston
Sudie E. Back
Peter Kalivas
Chee Ng
Richard A. Kanaan
机构：
[1] University of Melbourne,Department of Psychiatry, Austin Health
[2] University of Melbourne,Department of Psychiatry, The Melbourne Clinic
[3] Deakin University,IMPACT – the Institute for Mental and Physical Health and Clinical Translation, School of Medicine
[4] Barwon Health,Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, Florey Institute for Neuroscience and Mental Health and the Department of Psychiatry
[5] The University of Melbourne,Department of Psychiatry and Behavioral Sciences
[6] Austin Health,Department of Neuroscience
[7] Medical University of South Carolina; Ralph H. Johnson VA Medical Center,undefined
[8] Medical University of South Carolina,undefined
[9] Ralph H Johnson VA Medical Center,undefined
来源：
BMC Psychiatry | / 20卷
关键词：
Clinical trial protocol; N-acetyl cysteine; Post-traumatic stress disorder; N-acetyl cysteine; Adjunctive therapy; Randomised clinical trial; Oxidative stress; Biomarker;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial
    Klauser, Paul
    Xin, Lijing
    Fournier, Margot
    Griffa, Alessandra
    Cleusix, Martine
    Jenni, Raoul
    Cuenod, Michel
    Gruetter, Rolf
    Hagmann, Patric
    Conus, Philippe
    Baumann, Philipp S.
    Do, Kim Q.
    TRANSLATIONAL PSYCHIATRY, 2018, 8
  • [32] Simvastatin as an Adjunctive Therapy to Risperidone in Treatment of Autism: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
    Moazen-Zadeh, Ehsan
    Shirzad, Fatemeh
    Karkhaneh-Yousefi, Mohammad-Ali
    Khezri, Rasoul
    Mohammadi, Mohammad-Reza
    Akhondzadeh, Shahin
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2018, 28 (01) : 82 - 89
  • [33] Preliminary Results From a Multi-Centre, Double-Blind, Randomised Placebo Controlled Feasibility Trial of Add-on Sodium Benzoate and/or N-acetylcysteine in Patients With Early Schizophrenia
    Husain, Muhammad
    Chaudhry, Imran
    Khoso, Ameer Bukhsh
    Bassett, Paul
    Deakin, Bill
    Husain, Nusrat
    BIOLOGICAL PSYCHIATRY, 2022, 91 (09) : S299 - S299
  • [34] N-acetylcysteine augmentation therapy for moderate-to-severe obsessive-compulsive disorder: randomized, double-blind, placebo-controlled trial
    Paydary, K.
    Akamaloo, A.
    Ahmadipour, A.
    Pishgar, F.
    Emamzadehfard, S.
    Akhondzadeh, S.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2016, 41 (02) : 214 - 219
  • [35] Propolis as an adjunctive therapy for treatment of uncomplicated cystitis in women: A randomized double-blind placebo-controlled trial
    Shekari, Mahdi
    Hadi, Amir
    Daabo, Hamid Mahmood Abdullah
    Allahyari, Zahra Haj
    Hjazi, Ahmed
    Rafie, Nahid
    Heidari, Mohammad
    PHYTOTHERAPY RESEARCH, 2024, 38 (02) : 520 - 526
  • [36] Efficacy and tolerability of adjunctive gabapentin and memantine in obsessive compulsive disorder: Double-blind, randomized, placebo-controlled trial
    Farnia, Vahid
    Gharehbaghi, Haniyeh
    Alikhani, Mostafa
    Almasi, Afshin
    Golshani, Sanobar
    Tatari, Faeze
    Davarinejad, Omran
    Salemi, Safora
    Bahmani, Dena Sadeghi
    Holsboer-Trachsler, Edith
    Brand, Serge
    JOURNAL OF PSYCHIATRIC RESEARCH, 2018, 104 : 137 - 143
  • [37] Efficacy of pentoxifylline for the treatment of bipolar I/II patients with treatment-resistant depression: A proof-of-concept, randomized, double-blind, placebo-controlled trial
    Mohammad, Tavgah Ahmed Merza
    Mohammad, Talar Ahmed Merza
    Shawis, Teshk Nouri
    BRAIN RESEARCH BULLETIN, 2024, 216
  • [38] Effects of N-acetylcysteine supplementation on disease activity, oxidative stress, and inflammatory and metabolic parameters in rheumatoid arthritis patients: a randomized double-blind placebo-controlled trial
    Esalatmanesh, Kamal
    Jamali, Alireza
    Esalatmanesh, Roozbeh
    Soleimani, Zahra
    Khabbazi, Alireza
    Mahdavi, Aida Malek
    AMINO ACIDS, 2022, 54 (03) : 433 - 440
  • [39] Herbal medicine Davaie Loban in mild to moderate Alzheimer's disease: A 12-week randomized double-blind placebo-controlled clinical trial
    Tajadini, Haleh
    Saifadini, Rostam
    Choopani, Rasool
    Mehrabani, Mitra
    Kamalinejad, Mohammad
    Haghdoost, Ali Akbar
    COMPLEMENTARY THERAPIES IN MEDICINE, 2015, 23 (06) : 767 - 772
  • [40] Sildenafil adjunctive therapy to risperidone in the treatment of the negative symptoms of schizophrenia: a double-blind randomized placebo-controlled trial
    Akhondzadeh, Shahin
    Ghayyoumi, Raofeh
    Rezaei, Farzin
    Salehi, Bahman
    Modabbernia, Amir-Hossein
    Maroufi, Azad
    Esfandiari, Gholam-Reza
    Naderi, Mehrangiz
    Ghebleh, Fariba
    Tabrizi, Mina
    Rezazadeh, Shams-Ali
    PSYCHOPHARMACOLOGY, 2011, 213 (04) : 809 - 815
12345