A European network for virtual microscopy—design, implementation and evaluation of performance

被引:0
作者
Mikael Lundin
Janusz Szymas
Ewert Linder
Hans Beck
Peter de Wilde
Han van Krieken
Marcial García Rojo
Ignacio Moreno
Aurelio Ariza
Sitki Tuzlali
Sergülen Dervişoğlu
Heikki Helin
Veli-Pekka Lehto
Johan Lundin
机构
[1] University of Helsinki,Department of Oncology, Institute of Clinical Medicine
[2] Folkhälsan Research Center,Department of Clinical Pathology
[3] University of Medical Sciences,Department of Microbiology, Tumor, and Cell Biology (MTC)
[4] Swedish Institute for Infectious Disease Control (SMI),Department of Pathology
[5] Karolinska Institutet,Pathology Department
[6] Radboud University Nijmegen Medical Center,Department of Pathology
[7] Hospital General de Ciudad Real,Department of Pathology, Faculty of Medicine
[8] Hospital Universitari Germans Trias i Pujol,Cerrahpasa Medical Faculty, Pathology Department
[9] Istanbul University,Department of Pathology, Haartman Institute
[10] Istanbul University,undefined
[11] University of Helsinki and Helsinki University Central Hospital,undefined
[12] HUCH Laboratory Diagnostics,undefined
[13] Clinical Research Institute HUCH,undefined
来源
Virchows Archiv | 2009年 / 454卷
关键词
Virtual microscopy; Whole-slide imaging; Network; Internet; Pathology;
D O I
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中图分类号
学科分类号
摘要
Web-based virtual microscopy has enabled new applications within pathology. Here, we introduce and evaluate a network of academic servers, designed to maximize image accessibility to users from all regions of Europe. Whole-slide imaging was utilized to digitize the entire slide set (n = 154) for the slide seminars of the 21st European Congress of Pathology. The virtual slides were mirrored to five academic servers across Europe using a novel propagation method. Functionality was implemented that automatically selects the fastest server connection in order to optimize the slide-viewing speed (http://www.webmicroscope.net/ECP2007). Results show that during 6 months of monitoring the uptime of the network was 100%. The average viewing speed with the network was 3.1 Mbit/s, as compared to 1.9 Mbit/s using single servers. A good viewing speed (>2Mbit/s) was observed in 32 of 37 countries (86%), compared to 25 of 37 (68%) using single servers. Our study shows that implementing a virtual microscopy network spanning a large geographical area is technically feasible. By utilizing existing academic networks and cost-minimizing image compression, it is also economically feasible.
引用
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页码:421 / 429
页数:8
相关论文
共 29 条
[1]  
Steinberg DM(2001)Application of virtual microscopy in clinical cytopathology Diagn Cytopathol 25 389-96
[2]  
Ali SZ(2002)The virtual case: a new method to completely digitize cytological and histological slides Virchows Arch 441 159-64
[3]  
Demichelis F(2003)Use of virtual microscopy for didactic live-audience presentation in anatomic pathology Ann Diagn Pathol 7 67-72
[4]  
Barbareschi M(2004)A digital atlas of breast pathology: an application of web-based virtual microscopy J Clin Pathol 57 1288-1291
[5]  
Dalla Palma P(2005)Web-based virtual microscopy in teaching and standardizing Gleason grading Hum Pathol 36 381-6
[6]  
Romer DJ(2005)Resuscitating the teaching of anatomical pathology in undergraduate medical education: web-based innovative clinicopathological cases Pathology 37 360-363
[7]  
Suster S(2004)Virtual microscopy: applications in diagnostic pathology J Clin Pathol 57 1250-1251
[8]  
Lundin M(2003)Digital slide and virtual microscopy based routine and telepathology evaluation of routine gastrointestinal biopsy specimens J Clin Pathol 56 433-438
[9]  
Lundin J(2007)A randomized controlled trial of the diagnostic accuracy of internet-based telepathology compared with conventional microscopy Histopathology 50 266-273
[10]  
Helin H(2008)Image standards in tissue-based diagnosis (diagnostic surgical pathology) Diagn Pathol 3 17-undefined