Breast imaging technology Application of magnetic resonance imaging to angiogenesis in breast cancer

被引:0
作者
Martin O Leach
机构
[1] The Institute of Cancer Research and The Royal Marsden NHS Trust,CRC Clinical Magnetic Resonance Research Group
来源
Breast Cancer Research | / 3卷
关键词
angiogenesis; breast cancer; dynamic contrast enhanced imaging; magnetic resonance imaging; vascular permeability;
D O I
暂无
中图分类号
学科分类号
摘要
Magnetic resonance imaging (MRI) techniques enable vascular function to be mapped with high spatial resolution. Current methods for imaging in breast cancer are described, and a review of recent studies that compared dynamic contrast-enhanced MRI with histopathological indicators of tumour vascular status is provided. These studies show correlation between in vivo dynamic contrast measurements and in vitro histopathology. Dynamic contrast enhanced MRI is also being applied to assessment of the response of breast tumours to treatment.
引用
收藏
相关论文
共 152 条
[1]  
Folkman J(1992)The role of angiogenesis in tumor growth. Semin Cancer Biol 3 65-71
[2]  
Weidner N(1995)Current pathologic methods for measuring intra-tumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat 36 169-180
[3]  
Rankin SC(2000)MRI of the breast. Br J Radiol 73 806-818
[4]  
Kuhl CK(2000)MRI of breast tumors. Eur Radiol 10 46-58
[5]  
Orel SG(2000)MR imaging of the breast. Radiol Clin North Am 38 899-913
[6]  
Brown J(2000)Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study. Magn Reson Imaging 18 765-776
[7]  
Buckley D(1997)Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics. J Magn Reson Imaging 7 564-574
[8]  
Coulthard A(1999)Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 10 223-232
[9]  
Dixon AK(1998)MRIW: parametric analysis software for contrast-enhanced dynamic MR imaging in cancer. Radiographics 8 497-506
[10]  
Dixon JM(1997)Microvessel density of invasive breast cancer assessed by dynamic Gd-DTPA enhanced MRI. J Magn Reson Imaging 7 461-464