PCSK9 regulates myocardial ischemia–reperfusion injury through parkin/pink1-mediated autophagy pathway

被引：0
|
作者：
Guangwei Huang
Hailong Bao
Peng Zhan
Xiyang Lu
Zonggang Duan
Xinlin Xiong
Muzhi Lin
Bing Wang
Hongxin An
Luanda Xiahou
Haiyan Zhou
Zhenhua Luo
Wei Li
机构：
[1] The Affiliated Hospital of Guizhou Medical University,Department of Cardiovascular Medicine
[2] Anshun City People’s Hospital,Department of Cardiovascular Medicine
[3] Guizhou Medical University,Department of Central Lab
[4] Guizhou Provincial People’s Hospital,NHC Key Laboratory of Pulmonary Immune
[5] Guizhou Provincial People’s Hospital,Related Diseases
来源：
Molecular & Cellular Toxicology | 2024年 / 20卷
关键词：
PCSK9; Autophagy; Ischemia/reperfusion; Parkin/Pink1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：367 / 376
页数：9
相关论文
共 50 条
  • [1] PCSK9 regulates myocardial ischemia-reperfusion injury through parkin/pink1-mediated autophagy pathway
    Huang, Guangwei
    Bao, Hailong
    Zhan, Peng
    Lu, Xiyang
    Duan, Zonggang
    Xiong, Xinlin
    Lin, Muzhi
    Wang, Bing
    An, Hongxin
    Xiahou, Luanda
    Zhou, Haiyan
    Luo, Zhenhua
    Li, Wei
    MOLECULAR & CELLULAR TOXICOLOGY, 2024, 20 (02) : 367 - 376
  • [2] PCSK9 Knockdown Can Improve Myocardial Ischemia/Reperfusion Injury by Inhibiting Autophagy
    Huang, Guangwei
    Lu, Xiyang
    Duan, Zonggang
    Zhang, Kai
    Xu, Lei
    Bao, Hailong
    Xiong, Xinlin
    Lin, Muzhi
    Li, Chao
    Li, Yunquan
    Zhou, Haiyan
    Luo, Zhenhua
    Li, Wei
    CARDIOVASCULAR TOXICOLOGY, 2022, 22 (12) : 951 - 961
  • [3] Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin-Mediated Mitophagy
    Zhang, Yu
    Wang, Ziyi
    Jia, Chenyang
    Yu, Wenjie
    Li, Xiangdong
    Xia, Nan
    Nie, Huiling
    Wikana, Likalamu Pascalia
    Chen, Minhao
    Ni, Yong
    Han, Sheng
    Pu, Liyong
    CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2024, 17 (01): : 149 - 169
  • [4] PCSK9 Knockdown Can Improve Myocardial Ischemia/Reperfusion Injury by Inhibiting Autophagy
    Guangwei Huang
    Xiyang Lu
    Zonggang Duan
    Kai Zhang
    Lei Xu
    Hailong Bao
    Xinlin Xiong
    Muzhi Lin
    Chao Li
    Yunquan Li
    Haiyan Zhou
    Zhenhua Luo
    Wei Li
    Cardiovascular Toxicology, 2022, 22 : 951 - 961
  • [5] PCSK9 inhibition protects against myocardial ischemia-reperfusion injury via suppressing autophagy
    Huang, Guangwei
    Lu, Xiyang
    Zhou, Haiyan
    Li, Runhong
    Huang, Qing
    Xiong, Xinlin
    Luo, Zhenhua
    Li, Wei
    MICROVASCULAR RESEARCH, 2022, 142
  • [6] AM1241 alleviates myocardial ischemia-reperfusion injury in rats by enhancing Pink1/Parkin-mediated autophagy
    Liu, Wenhua
    Chen, Changgong
    Gu, Xingjian
    Zhang, Li
    Mao, Xiang
    Chen, Zili
    Tao, Luyuan
    LIFE SCIENCES, 2021, 272
  • [7] Gastrodin exerts perioperative myocardial protection by improving mitophagy through the PINK1/Parkin pathway to reduce myocardial ischemia-reperfusion injury
    Chen, Lu
    Lv, Yong
    Wu, Huiliang
    Wang, Yanting
    Xu, Zhenzhen
    Liu, Guoyang
    He, Yuyao
    Li, Xia
    Liu, Jie
    Feng, Yiqi
    Bai, Yunxiao
    Xie, Wanli
    Zhou, Quanjun
    Wu, Qingping
    PHYTOMEDICINE, 2024, 133
  • [8] OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy
    Zhao, Fan
    Zhu, Jiefu
    Zhang, Mingjiao
    Luo, Yanwen
    Li, Yuzhen
    Shi, Lang
    Huang, Jing
    Shadekejiang, Halinuer
    Dong, Shengyu
    Wu, Xiongfei
    CELL PROLIFERATION, 2023, 56 (08)
  • [9] Dexmedetomidine improves myocardial ischemia-reperfusion injury by increasing autophagy via PINK1/PRKN pathway
    Liu, Lu
    Ji, Xiaojun
    Huang, Xumei
    SIGNA VITAE, 2022, 18 (05) : 125 - 132
  • [10] HYPERBILIRUBINEMIA AGGRAVATES RENAL ISCHEMIA REPERFUSION INJURY BY EXACERBATING PINK1-PARKIN-MEDIATED MITOPHAGY
    Liao, Pingping
    Wang, Xiaoyu
    Dong, He
    Chai, Dongyue
    Yue, Ziqi
    Lyu, Lin
    SHOCK, 2023, 60 (02): : 262 - 271
12345