Lacrimal Gland Adenoid Cystic Carcinoma with High-Grade Transformation to Myoepithelial Carcinoma: Report of a Case and Review of Literature

被引：23

作者：

Argyris P.P. ^{[1
]}

Pambuccian S.E. ^{[2
]}

Cayci Z. ^{[3
]}

Singh C. ^{[2
]}

Tosios K.I. ^{[1
]}

Koutlas I.G. ^{[4
]}

机构：

[1] Department of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens, Athens

[2] Department of Laboratory Medicine and Pathology, University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN

[3] Department of Diagnostic Radiology, University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN

[4] Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN, 515 Delaware Street

来源：

Head and Neck Pathology | 2013年 / 7卷 / 1期

关键词：

Adenoid cystic carcinoma; High grade transformation; Immunohistochemistry; Lacrimal gland; Pathology;

D O I：

10.1007/s12105-012-0383-2

中图分类号：

学科分类号：

摘要：

Adenoid cystic carcinoma (AdCC) is the most frequent malignant neoplasm of the lacrimal glands. Like its salivary gland counterpart, lacrimal AdCC can rarely undergo high-grade transformation ("dedifferentiation"). We herein report the clinical, radiographic and microscopic findings of a lacrimal gland AdCC with high grade transformation, occurring in a 39-year-old female patient. In contrast to salivary gland AdCC with high-grade transformation, which usually shows a high grade component with "ductal" differentiation, in the case presented, the "dedifferentiated" component showed morphologic and immunohistochemical features of myoepithelial differentiation. © 2012 Springer Science+Business Media, LLC.

引用

页码：85 / 92

页数：7

共 29 条

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