Ubiquitination, proteasomes and GABAA receptors

被引：0
|
作者：
Bernhard Lüscher
Cheryl A. Keller
机构：
[1] Pennsylvania State University,Department of Biology and the Department of Biochemistry and Molecular Biology
来源：
Nature Cell Biology | 2001年 / 3卷
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摘要：
Inhibitory neurotransmission by γ-aminobutyric acid (GABA) is regulated by the number and subcellular localization of GABAA receptors in the membrane of the target neuron. A new study suggests that the ubiquitin-like protein Plic-1 stabilizes intracellular GABAA receptors and promotes their accumulation in the plasma membrane.
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页码：E232 / E233
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