Continuous Monitoring of Middle Cerebral Artery Recanalization with Transcranial Color-Coded Sonography and Levovist

被引:0
作者
Alain Viguier
Raphael Petit
Mathieu Rigal
Pascal Cintas
Vincent Larrue
机构
[1] University of Toulouse,Department of Neurology
[2] Service de Neurologie,undefined
[3] Hôpital de Rangueil,undefined
来源
Journal of Thrombosis and Thrombolysis | 2005年 / 19卷
关键词
ultrasound; thrombolysis; acute stroke;
D O I
暂无
中图分类号
学科分类号
摘要
Background and purpose: Treatment of acute ischemic stroke with intravenous recombinant tissue plasminogen activator (rtPA) is relatively ineffective in patients with large vessel occlusion. Numerous experimental studies have demonstrated that ultrasound (US) can accelerate enzymatic fibrinolysis and acceleration of lysis by US is enhanced in the presence of microbubbles used as echo-contrast agents. The purpose of this study was to evaluate the feasibility of continuous monitoring of middle cerebral artery (MCA) recanalization using transcranial color-coded sonography (TCCS) and intravenously administered microbubbles.
引用
收藏
页码:55 / 59
页数:4
相关论文
共 92 条
  • [1] Wardlaw JM(1995)Tissue plasminogen activator for acute ischemic stroke New Engl J Med 333 1581-1587
  • [2] Sandercock P(2003)Thrombolytic therapy with recombinant tissue plasminogen activator for acute ischemic stroke: Where do we go from here? A cumulative meta-analysis Stroke 34 1437-1442
  • [3] Berge E(1992)Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke Ann Neurol 32 78-86
  • [4] Del Zoppo GJ(1995)Does arterial recanalization improve outcome in carotid territory stroke? Stroke 26 581-587
  • [5] Poeck K(2000)High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial Doppler Stroke 31 610-614
  • [6] Pessin MS(2002)High rate of recanalization of middle cerebral artery occlusion during 2-MHz transcranial color-coded doppler continuous monitoring without thrombolytic drug Stroke 33 626-628
  • [7] von Kummer R(2003)Effect of ultrasound on thrombolysis of middle cerebral artery occlusion Ann Neurol 53 797-800
  • [8] Holle R(2004)Ultrasound-enhanced thrombolysis for acute ischemic stroke: Phase I. findings of the CLOTBUST trial J Neuroimaging 14 113-117
  • [9] Rosin L(2004)Differentoal pattern of tissue plasminogen activator-induced proximal middle cerebral artery recanalization among stroke subtypes Stroke 35 486-490
  • [10] Forsting M(1995)Spontaneous middle cerebral artery reperfusion in ischemic stroke. A follow-up study with transcranial Doppler Stroke 26 430-433