Design, synthesis, and evaluation of novel 1-methyl-3-substituted quinazoline-2,4-dione derivatives as antimicrobial agents

被引：0
|
作者：
Qing-Gang Ji
Dan Yang
Qiao Deng
Zhi-Qiang Ge
Lv-Jiang Yuan
机构：
[1] Southwest University,School of Chemistry and Chemical Engineering
来源：
Medicinal Chemistry Research | 2014年 / 23卷
关键词：
Quinazoline-2,4-dione; Amide; Antibacterial; Antifungal agents;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of novel 1-methyl-3-substituted quinazoline-2,4-dione derivatives was designed, synthesized, and evaluated for their antimicrobial activities against six strains of bacteria and five fungi in vitro. The synthesized compounds were characterized by spectral methods. The bioactive assays showed that most of the compounds exhibited moderate antimicrobial activities against the tested strains.
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页码：2169 / 2177
页数：8
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