Structural and functional changes in the zebrafish (Danio rerio) skeletal muscle after cadmium exposure

被引：0
作者：
Bice Avallone
Claudio Agnisola
Raimondo Cerciello
Raffaele Panzuto
Palma Simoniello
Patrizia Cretì
Chiara Maria Motta
机构：
[1] University of Naples Federico II,Department of Biology
[2] GSI Helmholtz Center for Heavy Ion Research,Department of Biophysics
[3] University of Salento,Department of Biological and Environmental Sciences and Technologies
来源：
Cell Biology and Toxicology | 2015年 / 31卷
关键词：
Behavioral tests; Cadmium; Lectins; Toxicity; Ultrastructure; Ucrit;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This report describes the alterations induced by an environmentally realistic concentration of cadmium in skeletal muscle fibre organization, composition, and function in the teleost zebrafish. Results demonstrate that the ion induces a significant quantitative and qualitative deterioration, disrupting sarcomeric pattern and altering glycoprotein composition. These events, together with a mitochondrial damage, result in a significant reduction in swimming performance. In conclusion, the evidence here collected indicate that in presence of an environmental cadmium contamination, important economic (yields in fisheries/aquaculture), consumer health (fish is an important source of proteins), and ecological (reduced fitness due to reduced swimming performance) consequences can be expected.
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页码：273 / 283
页数：10
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