Combined kyphoplasty and intraoperative radiotherapy (Kypho-IORT) versus external beam radiotherapy (EBRT) for painful vertebral metastases - a randomized phase III study

[1] Gerszten PC(2009)Radiotherapy and radiosurgery for metastatic spine disease: what are the options, indications, and outcomes? Spine 34 78-92

[2] Mendel E(2009)DEGRO practice guidelines for palliative radiotherapy of metastatic breast cancer: bone metastases and metastatic spinal cord compression (MSCC) Strahlenther Onkol 185 417-424

[3] Yamada Y(2005)Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases J Natl Cancer Inst 97 798-804

[4] Souchon R(2006)Prospective randomised multicenter trial on single fraction radiotherapy (8 Gy x 1) versus multiple fractions (3 Gy x 10) in the treatment of painful bone metastases Radiother Oncol 79 278-284

[5] Wenz F(1999)8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12 months of patient follow-up Radiother Oncol 52 111-121

[6] Sedlmayer F(2011)Cancer Patient Fracture Evaluation (CAFE) Investigators: balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial Lancet Oncol 12 225-235

[7] Budach W(2011)Development of a novel method for intraoperative radiotherapy during kyphoplasty for spinal metastases (Kypho-IORT) Int J Radiat Oncol Biol Phys 81 1114-1119

[8] Dunst J(2010)Kypho-IORT – a novel approach of intraoperative radiotherapy during kyphoplasty for vertebral metastases Radiat Oncol 5 11-1260

[9] Feyer P(2012)Kyphoplasty and intra-operative radiotherapy, combination of kyphoplasty and intra-operative radiation for spinal metastases: technical feasibility of a novel approach Int Orthop 36 1255-440

[10] Hartsell WF(2012)Intraoperative radiotherapy during kyphoplasty for vertebral metastases (Kypho-IORT): first clinical results Tumori 98 434-253

[1] Gerszten PC(2009)Radiotherapy and radiosurgery for metastatic spine disease: what are the options, indications, and outcomes? Spine 34 78-92

[2] Mendel E(2009)DEGRO practice guidelines for palliative radiotherapy of metastatic breast cancer: bone metastases and metastatic spinal cord compression (MSCC) Strahlenther Onkol 185 417-424

[3] Yamada Y(2005)Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases J Natl Cancer Inst 97 798-804

[4] Souchon R(2006)Prospective randomised multicenter trial on single fraction radiotherapy (8 Gy x 1) versus multiple fractions (3 Gy x 10) in the treatment of painful bone metastases Radiother Oncol 79 278-284

[5] Wenz F(1999)8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12 months of patient follow-up Radiother Oncol 52 111-121

[6] Sedlmayer F(2011)Cancer Patient Fracture Evaluation (CAFE) Investigators: balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial Lancet Oncol 12 225-235

[7] Budach W(2011)Development of a novel method for intraoperative radiotherapy during kyphoplasty for spinal metastases (Kypho-IORT) Int J Radiat Oncol Biol Phys 81 1114-1119

[8] Dunst J(2010)Kypho-IORT – a novel approach of intraoperative radiotherapy during kyphoplasty for vertebral metastases Radiat Oncol 5 11-1260

[9] Feyer P(2012)Kyphoplasty and intra-operative radiotherapy, combination of kyphoplasty and intra-operative radiation for spinal metastases: technical feasibility of a novel approach Int Orthop 36 1255-440

[10] Hartsell WF(2012)Intraoperative radiotherapy during kyphoplasty for vertebral metastases (Kypho-IORT): first clinical results Tumori 98 434-253